ABSTRACT
Dendrimers are new polymeric architectures that have specified topologies and are versatile in drug delivery with high functionality. Dendrimers have been effectively employed to improve the solubilization of poorly soluble medicines in several investigations. Dendrimers are well-defined, homogeneous, monodisperse, and radially symmetric nanoscale molecules having a branch-like structure. On a molecular level, dendritic branching produces globular to semi-globular structures with a constrained molecular “volume” and a high density of surface functions. Dendrimers are ideal for medication delivery systems due to their unique characteristics. Dendrimers are a brand-new type of polymeric material. The manufacture of many dendrimers using a divergent strategy is successful. Defects in the structure are caused by side reactions and insufficient reactivity of the end groups. Dendrimer synthesis has been the subject of numerous reports. The double exponential growth approach, developed by Moore in 1995, represents a key advance in the synthesis of the dendrimer.
