ABSTRACT

Nowadays, phytoconstituents are receiving significant attention due to their impeccable ability to treat almost all disease conditions, such as cancer, Alzheimer’s, Parkinson’s, ischemic stroke, atherosclerosis, chronic wounds, diabetes mellitus, obesity, etc. Some common phytoconstituents widely recognized for their efficient biomedical applications include resveratrol, curcumin, berberine, apigenin, epigallocatechin gallate, quercetin, and so on. Although these phytochemicals are cost-effective, with relatively fewer side effects than synthetic chemicals, their therapeutic efficacy is not greater than many synthetic chemicals. One of the primary reasons behind these issues is poor bioavailability, short half-life, poor stability in environmental and physiological conditions, lack of prolonged effect, and no targeting ability. Nanotechnology has emerged in recent years in the quest to overcome these drawbacks. Nanotechnology involves the engineering of nanomaterials in the nanosize range. Among many nanomaterials, polymer-based NPs have grasped the attention due to their ability to achieve controlled and targeted drug delivery, long-term stability, and biocompatibility. In addition, the scale-up of these NPs is straightforward compared to other NPs. In this contemplate, the present chapter describes different types of polymer-based NPs. Further, it meticulously discusses the role of polymer-based nanophytomedicine in various biomedical applications.