ABSTRACT
Gene therapy is a promising technique that focuses on the utilisation of genes to treat or prevent diseases ranging from single gene disorder to multi-gene disorder. The experimental approaches of gene therapy may authorise doctors to treat any diseases by introducing a gene into patient’s cells in place of surgery or drugs. Gene therapy looks to alter genes to ameliorate genetic defects and cure genetic diseases. A gene delivery system is essential to treat genetic diseases. Gene delivery is a process of delivering genetic materials such as nucleic acid into the patient’s cells to generate the therapeutic effect. Dendrimers have capability to form polycations under various physiological conditions with the ability to bind genetic molecules containing negative charge, and they also interact with anionic groups of the nucleic acid. Dendrimers are novel gene delivery vectors belonging to the class of non-viral polymeric vectors.
