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Refractory obsessive-compulsive disorder: a challenging treatment

Published online by Cambridge University Press:  01 September 2022

A.L. Ramos  and
H. Salgado
A.L. Ramos*
Affiliation:
Centro Hospitalar Universitário de São João, Psiquiatria, Porto, Portugal
H. Salgado
Affiliation:
Centro Hospitalar Universitário de São João, Psiquiatria, Porto, Portugal
*
*Corresponding author.

Abstract

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Introduction

Obsessive-compulsive disorder (OCD) is a chronic and impairing condition included in the DSM-5 Obsessive-Compulsive Spectrum Disorders. Despite psychopharmacological and psychotherapeutic measures, there are patients who remain refractory to different therapeutic strategies.

Objectives

The authors aim to present different alternatives in approach, treatment and management of refractory OCD, based on a review of the existing literature.

Methods

Analysis of the data about this subject, considering the review articles and the case reports published at current time and highlighting the most essential topics, concerning the latest developments in the area.

Results

Therapeutic options are presented, including transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), deep brain stimulation (DBS) and ablative neurosurgery.

Conclusions

The treatment of OCD represents a great challenge in clinical practice. Despite the advances accomplished by a more extensive knowledge of the disease and a burden of new techniques in the last decades, more treatment strategies are needed, especially for patients with non-response to conventional treatment.

Disclosure

No significant relationships.

Keywords

Deep brain stimulationtranscranial direct current stimulationobsessive-compulsive disorderrepetitive transcranial magnetic stimulation
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S295
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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