抗肿瘤血管生成治疗的纳米递送策略

Strategies of nano drug delivery system applied in anti-angiogenic therapy

摘要: 抗肿瘤血管生成治疗应用范围广泛，恰如其分地运用纳米递药系统能够在发挥抗血管生成作用的同时达到增效减毒的效果。本文综述了纳米递药系统在抗肿瘤血管生成治疗中的应用，介绍了各类纳米粒子提高抗血管生成治疗疗效的策略与设计思路，以期为抗肿瘤血管生成治疗的深入研究提供理论参考。

Abstract: Anti-angiogenic therapy has a wide range of applications in the treatment of tumor. Nano drug delivery system can contribute to higher efficacy and lower toxicity in anti-angiogenic therapy. This article reviews the application of nano drug delivery system in anti-angiogenic therapy and introduces the strategies to improve its treatment efficiency with varieties of nanoparticles, providing reference for the development of anti-angiogenic therapy.