Multifrequency Immittancemetry in Experimentally Induced Stapes, Round Window and Cochlear Lesions

Vol. 12, No. 2, 2007

Free Abstract Article (Fulltext) Article (PDF 401 KB)

Original Paper

Multifrequency Immittancemetry in Experimentally Induced Stapes, Round Window and Cochlear Lesions
Vincent Darrouzet^a, Didier Dulon^b, Valérie Franco-Vidal^a

^aOtolaryngology and Skull Base Surgery Department and
^bHearing Molecular Biology Research Institute, University of Bordeaux 2 Victor Ségalen, Bordeaux, France

Address of Corresponding Author

Audiol Neurotol 2007;12:85-100 (DOI: 10.1159/000097795)

Key Words

Multifrequency tympanometry
Tympanometry
Impedance audiometry
Cochlea
Perilymphatic fistula
Acoustic trauma

Abstract

Objectives: To establish that admittance (Y) and susceptance (B) conductance (G) tympanograms at 2 kHz can reflect the status of the annular ligament and the cochlear pressure. Methods: Seven experiments were set up in 22 guinea pigs: ventilation of the bulla, blockage of the stapes and round window membrane (RWM), fistula, fluid removal from the cochlea, injection of saline in the scala tympani and acoustic trauma. Resonance frequency, Y, B and G at 2 kHz and curve shapes were analyzed before and after lesions. Results: A supplementary peak was observed in Y/G tympanograms in all RWM fistulas and in some cases of acoustic trauma; injection of saline into the scala tympani induced constant, immediate and reproducible changes; RWM and stapes blockages induced foreseeable peaking at 2 kHz; fluid removal from the cochlea induced multiple peak curves. Conclusion: Experimentally induced modifications at the AL result in noticeable, constant and reproducible changes in tympanogram curves at 2 kHz and seem to reflect inner ear pressure.

Author Contacts

Prof. Vincent Darrouzet
Service ORL, Hôpital Pellegrin, Place Amélie Raba-Léon
FR-33076 Bordeaux Cedex (France)
Tel. +33 556 79 55 32, Fax +33 556 79 87 80
E-Mail vincent.darrouzet@chu-bordeaux.fr

Article Information

This paper was accepted and presented at the 5th International Symposium on Ménière's Disease and Inner Ear Homeostasis Disorders, held in Los Angeles, April 2-5, 2005.

Received: March 29, 2006
Accepted after revision: August 30, 2006
Published online: December 6, 2006
Number of Print Pages : 16
Number of Figures : 12, Number of Tables : 3, Number of References : 33

Medline Abstract (ID 17264472)

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