Vol. 20, No. 4, 2005
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Original Paper
The Natural History of Radiographically Defined Vertebrobasilar Nonsaccular Intracranial Aneurysms
Kelly D. Flemminga, David O. Wiebersa, Robert D. Brown,Jr.a, Michael J. Linkb, John Huston, IIIc, Robyn L. McClellandd, Teresa J.H. Christiansond
Departments of
aNeurology,
bNeurosurgery, and
cDiagnostic Radiology, and
dDivision of Biostatistics, Mayo Clinic College of Medicine, Rochester, Minn., USA
Address of Corresponding Author
Cerebrovasc Dis 2005;20:270-279 (DOI: 10.1159/000087710)
![goto top of page](Showpic.asp?filename="/images/global/odstop.gif") Key Words
- Aneurysm
- Basilar
- Dolichoectasia
- Fusiform
- Stroke
Abstract
Background: Vertebrobasilar nonsaccular intracranial aneurysms (VBNIA) are characterized by dilatation, elongation, and tortuosity of the vertebrobasilar system. Methods:The medical records and imaging of patients with vertebrobasilar fusiform aneurysms or dolichoectasia between 1989 and 2001 were reviewed. Prospective follow-up was obtained. Results: One hundred and fifty-nine patients were identified (74% male) with 719 patient years of follow-up. Presenting events included: hemorrhage (3%), ischemia (28%), and compression (22%). The remainder were incidental. The 1-, 5-, and 10-year risk of cerebral infarction (CI) due toVBNIA is 2.7, 11.3, and 15.9% respectively. The risk of recurrent CI is 6.7% per patient year. Median survival was 7.8 years and death was most commonly due to ischemia. Conclusions:VBNIA are more common in men and typically present in the 6-7th decade. Recurrent CI is more common than hemorrhage risk. Copyright © 2005 S. Karger AG, Basel
Author Contacts
Kelly D. Flemming, MD
Mayo Clinic College of Medicine, Department of Neurology, W8B
200 First Street SW
Rochester, MN 55905 (USA)
Tel. +1 507 538 1036, Fax +1 507 266 4419, E-Mail flemming.kelly@mayo.edu
Article Information
Received: March 22, 2005
Accepted: June 9, 2005
Published online: August 22, 2005
Number of Print Pages : 10
Number of Figures : 4, Number of Tables : 3, Number of References : 18 |
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