Atypical Poorly Differentiated Cutaneous T-Cell Lymphoma with an Angiocentric Growth Pattern Presenting Histologically as Vasculitis

Vol. 210, No. 4, 2005

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Case Report

Atypical Poorly Differentiated Cutaneous T-Cell Lymphoma with an Angiocentric Growth Pattern Presenting Histologically as Vasculitis
B. Laetsch, G. Hofbauer, W. Kempf, G. Burg, R. Dummer

Dermatologische Klinik, Universitätsspital Zürich, Zürich, Schweiz

Address of Corresponding Author

Dermatology 2005;210:341-345 (DOI: 10.1159/000084763)

Key Words

Cutaneous T-cell lymphoma
Angiocentric growth pattern
Paraneoplastic vasculitis

Abstract

We report the case of a 41-year-old patient with an aggressive cutaneous T-cell lymphoma (CTCL) initially presenting on histology as lymphocytic vasculitis. On repeated histological examination and by molecular biology work-up, the diagnosis of an unclassifiable CTCL could eventually be established. This atypical poorly differentiated lymphoma was of a CD4+ CD8- CD56- phenotype and followed an unfavourable course. The patient died despite chemo- and immunotherapy 7 months after the first consideration of lymphoma as diagnosis.

Author Contacts

Prof. Reinhard Dummer
Dermatologische Klinik, Universitätsspital Zürich
Gloriastrasse 31
CH-8091 Zürich (Switzerland)
Tel. +41 44 255 25 07, Fax +41 44 255 89 88, E-Mail reinhard.dummer@usz.ch

Article Information

Received: April 22, 2004
Accepted: September 24, 2004
Number of Print Pages : 5
Number of Figures : 5, Number of Tables : 0, Number of References : 28

Medline Abstract (ID 15942225)

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