Chronic Unilateral Ureteral Obstruction Represented as Renin-Dependent Hypertension

Vol. 85, No. 2, 2000

Free Abstract Article (Fulltext) Article (PDF 190 KB)

Case Report

Chronic Unilateral Ureteral Obstruction Represented as Renin-Dependent Hypertension
Shigeto Ishidoya^a, Atsushi Fukuzaki^a, Hiroyuki Kaneto^a, Atsushi Takeda^a, Yukihiko Ogata^a, Toru Sasaki^a, Ken-ichi Suzuki^a, Ryuji Watanabe^a, Senji Hoshi^a, Masahiro Kikuya^b, Kazuhisa Takeuchi^b, Sadayoshi Ito^b, Seiichi Orikasa^a

^aDepartment of Urology and
^bSecond Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan

Address of Corresponding Author

Nephron 2000;85:175-177 (DOI: 10.1159/000045651)

Key Words

Unilateral ureteral obstruction
Hypertension
Renin

Abstract

A 50-year-old woman developed renin-dependent hypertension immediately after accidental unilateral ureteral ligation during hysterectomy, and the hypertension lasted for 5 months. Surgical release of the obstruction was carried out 157 days after the ligation. Then, her blood pressure was normalized. However, the obstructed kidney showed intensive tubulointerstitial fibrosis and functional recovery was not obtained. This case suggests that the renin-angiotensin system may be upregulated in human kidney during unilateral ureteral obstruction for a long duration.

Author Contacts

Shigeto Ishidoya, MD
Department of Urology, Tohoku University School of Medicine
1-1 Seiryo-machi, Aoba-ku
Sendai 980-8574 (Japan)
Tel. +81 22 717 7278, Fax +81 22 717 7283, E-Mail ishidoya@mail.cc.tohoku.ac.jp

Article Information

Accepted: September 29, 1999
Number of Print Pages : 3
Number of Figures : 3, Number of Tables : 0, Number of References : 14

Medline Abstract (ID 10867524)

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