Paper

A baboon (Papio hamadryas) with an isochromosome for the long arm of the X
C.M. Moore^a, M.M. Leland^b, R.G. Brzyski^a, J. McKeand^a, S.M. Witte^b, J. Rogers<sup>b

a</sup>University of Texas Health Science Center at San Antonio and
^bSouthwest Foundation for Biomedical Research, San Antonio, TX (USA)

Address of Corresponding Author

Cytogenet Cell Genet 1998;82:80-82 (DOI: 10.1159/000015069)

  Abstract.

A 5.5-yr-old female baboon was evaluated for sexual immaturity. She was small for her age and had normal external female genitalia. However, she lacked cyclical perineal turgescence and displayed atypical coloration of the perineal skin. Laparoscopy revealed a small uterus and absence of both ovaries. Cytogenetic analysis revealed a 42,X,i(X)(q10) karyotype. DNA analysis using loci DXS1683, which maps to Xp22.1, and DXS297, which maps to Xq27.3, was consistent with inheritance of the normal X chromosome from the dam and formation of the isochromosome Xq from the paternal X.

  Author Contacts

Request reprints from Dr. Charleen M. Moore, Department of Cellular andStructural Biology, University of Texas Health Science Center atSan Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284-7836 (USA);telephone: 210-567-3875; fax: 210-567-4963; e-mail: moorec@uthscsa.edu.

  Article Information

Received: Received 14 November 1998;
revision accepted 22 June 1998.
Number of Print Pages : 3
Number of Figures : 3, Number of Tables : 0, Number of References : 12