Abstract
Interactions between sinefungin and copper(II) ions were investigated. Stoichiometry and stability
constants of the metal-free system and two mononuclear complexes present in solution were determined on the basis
of potentiometric data analysis. The results were compared to the Cu(II)-ornithine system due to structural similarities
between both molecules. Combined spectroscopic and theoretical studies allowed for determination of coordination
pattern for the Cu(II)-sinefungin complexes. At acidic pH, copper is bound in “glycine-like” coordination
mode, identical with that of ornithine. This involves