Simone Balocco
ABSTRACT
In this paper, we present a complete framework that automatically provides fluid-dynamic and plaque analysis from IVUS and Angiographic sequences. Such framework is used to analyze, in three coronary arteries, the relation between wall shear stress with type and amount of plaque. Preliminary qualitative results show an inverse relation between the wall shear stress and the plaque burden, which is confirmed by the fact that the plaque growth is higher on the wall having concave curvature. Regarding the plaque type it was observed that regions having low shear stress are predominantly fibro-lipidic while the heavy calcifications are in general located in areas of the vessel having high WSS.
- Simone Balocco, Carlo Gatta, Francesco Ciompi, Oriol Pujol, Xavier Carrillo, Josepa Mauri, and Petia Radeva. Combining Growcut and Temporal Correlation for IVUS Lumen Segmentation, volume 6669 of Lecture Notes in Computer Science, pages 556--563. Springer Berlin/Heidelberg, 2011. Google Scholar
Digital Library
- C. V. Bourantas, I. C. Kourtis, M. E. Plissiti, D. I. Fotiadis, C. S. Katsouras, M. I. Papafaklis, and L. K. Michalis. A method for 3d reconstruction of coronary arteries using biplane angiography and intravascular ultrasound images. Comput Med Imaging Graph, 29(8): 597--606, Dec 2005.Google ScholarCross Ref
- C. Canero, F. Vilarino, J. Mauri, and P. Radeva. Predictive (un)distortion model and 3-d reconstruction by biplane snakes. IEEE Trans Med Imaging, 21(9):1188--201, Sep 2002.Google ScholarCross Ref
- F. Ciompi, O. Pujol, C. Gatta, O. Rodríguez-Leor, J. Mauri-Ferré, and P. Radeva. Fusing in-vitro and in-vivo intravascular ultrasound data for plaque characterization. International Journal of Cardiovascular Imaging, (in press), 2009.Google Scholar
- F. Ciompi, O. Pujol, C. Gatta, Xavier Carrillo, J. M. Ferre, and P. Radeva. A holistic approach for the detection of media-adventitia border in ivus. volume (in press), 2011.Google Scholar
- Laurent Cohen and Ron Kimmel. Global minimum for active contour models: A minimal path approach. International Journal of Computer Vision, 24:57--78, 1997. Google ScholarDigital Library
- Jouke Dijkstra and Stephane Carlier. Accurate plaque volume measurements in 3d reconstructed ivus pullback sequences. The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging), 19(4):313-314-314, 2003. ISSN 1569-5794.Google Scholar
- C. Gatta, S. Balocco, F. Ciompi, R. Hemetsberger, O. Rodriguez Leor, and P. Radeva. Real-time gating of ivus sequences based on motion blur analysis: method and quantitative validation. Med Image Comput Comput Assist Interv, 13(Pt 2):59--67, 2010. Google ScholarDigital Library
- K. R. Hoffmann, A. Wahle, C. Pellot-Barakat, J. Sklansky, and M. Sonka. Biplane x-ray angiograms, intravascular ultrasound, and 3d visualization of coronary vessels. Int J Card Imaging, 15(6):495--512, Dec 1999.Google ScholarCross Ref
- H. Huang, R. Virmani, H. Younis, A. P. Burke, R. D. Kamm, and R. T. Lee. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation, 103(8):1051--6, Feb 27 2001.Google ScholarCross Ref
- J. D. Humphrey. Mechanisms of arterial remodeling in hypertension. coupled roles of wall shear and intramural stress. Hypertension, 52: 195, 2008.Google ScholarCross Ref
- S. D. Ramaswamy, S. C. Vigmostad, A. Wahle, Y. G. Lai, M. E. Olszewski, K. C. Braddy, T. M. Brennan, J. D. Rossen, M. Sonka, and K. B. Chandran. Fluid dynamic analysis in a human left anterior descending coronary artery with arterial motion. Ann Biomed Eng, 32 (12):1628--41, Dec 2004.Google ScholarCross Ref
- S. D. Ramaswamy, S. C. Vigmostad, A. Wahle, Y. G. Lai, M. E. Olszewski, K. C. Braddy, T. M. Brennan, J. D. Rossen, M. Sonka, and K. B. Chandran. Comparison of left anterior descending coronary artery hemodynamics before and after angioplasty. J Biomech Eng, 128(1):40--8, Feb 2006.Google ScholarCross Ref
- D. Rotger, M. Rosales, J. Garcia, O. Pujol, J. Mauri, and P. Radeva. Active vessel: A new multimedia workstation for intravascular ultrasound and angiography fusion. Computers in Cardiology, 30:65--68, 2003 2003.Google Scholar
- H. Samady, P. Eshtehardi, M. C. McDaniel, J. Suo, S. S. Dhawan, C. Maynard, L. H. Timmins, A. A. Quyyumi, and D. P. Giddens. Coronary artery wall shear stress is associated with progression and transformation of atherosclerotic plaque and arterial remodeling in patients with coronary artery disease. Circulation, 124(7):779--88, Aug 16.Google ScholarCross Ref
- C. J. Slager, J. J. Wentzel, J. C. Schuurbiers, J. A. Oomen, J. Kloet, R. Krams, C. von Birgelen, W. J. van der Giessen, P. W. Serruys, and P. J. de Feyter. True 3-dimensional reconstruction of coronary arteries in patients by fusion of angiography and ivus (angus) and its quantitative validation. Circulation, 102(5):511--6, Aug 1 2000.Google ScholarCross Ref
- V. Vezhnevets and V. Konouchine. Grow-cut" - interactive multi-label n-d image segmentation. pages 150--156, 2005.Google Scholar
- A. Wahle, M. E. Olszewski, and M. Sonka. Interactive virtual endoscopy in coronary arteries based on multimodality fusion. IEEE Trans Med Imaging, 23(11):1391--403, Nov 2004.Google ScholarCross Ref
- A. Wahle, J. J. Lopez, M. E. Olszewski, S. C. Vigmostad, K. B. Chandran, J. D. Rossen, and M. Sonka. Plaque development, vessel curvature, and wall shear stress in coronary arteries assessed by x-ray angiography and intravascular ultrasound. Med Image Anal, 10(4): 615--31, Aug 2006.Google ScholarCross Ref
- Andreas Wahle. Quantification of coronary hemodynamics and plaque morphology using x-ray angiography and intravascular ultrasound. International Congress Series, 1268:1035--1039, 2004. ISSN 0531--5131.Google ScholarCross Ref
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