Ultrasound Thermotherapy of Breast: Theoretical Design of Transducer and Numerical Simulation of Procedure

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Published 8 March 2006 Copyright (c) 2006 The Japan Society of Applied Physics
, , Citation Behnia Sohrab et al 2006 Jpn. J. Appl. Phys. 45 1856 DOI 10.1143/JJAP.45.1856

1347-4065/45/3R/1856

Abstract

The absorbed ultrasound energy is changed into heat in a dissipative medium. This could be of great advantage in treating tumors in a noninvasive manner, by raising their temperature to cytotoxic levels. In this study we investigated whether using a fixed-focus transducer can destroy breast tumor cells, especially in early stages, in a cost-effective manner and reduce treatment time significantly. An appropriate fixed-focus transducer was designed, and the resultant acoustic pressure was calculated by solving the Rayleigh integral. A two-dimensional breast model was constructed from the magnetic resonance image (MRI) of a cancerous breast. Then, the induced temperature elevation was calculated using the bioheat equation and applying the finite element method (FEM) to the model. Results demonstrate that this transducer can generate a temperature of up to 61 °C in 3 s, which is sufficient to destroy cancer cells, particularly in early stages.

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10.1143/JJAP.45.1856