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Bilayer properties of giant magnetic liposomes formed by cationic pyridine amphiphile and probed by active deformation under magnetic forces

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Abstract.

We synthesize giant magnetic liposomes by a reverse-phase evaporation method (REV) using a new self-assembling Cationic Pyridine Amphiphile (CPA) derived from 1,4-dihydropyridine as liposome-forming agent and a magnetic ferrofluid based on \( \gamma\) - Fe 2 O 3 nanoparticles. Having in view the potential interest of CPA in targeted transport by magnetic forces, the mechanical elastic properties of such bilayers are here directly investigated in vesicles loaded with magnetic nanoparticles. Bending elastic modulus K b ∼ 0.2 to 5k B T and pre-stress \( \tau_{0}\) ∼ 3.2 to 12 . 10-6 erg/cm 2 are deduced from the under-field deformations of the giant magnetic liposomes. The obtained Kb values are discussed in terms of A. Wurgers's theory.

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Authors and Affiliations

  1. University of Latvia, Zeļļu-8, LV-1002, Rıga, Latvia

    O. Petrichenko, K. Ērglis & A. Cēbers

  2. Institute of Organic Synthesis, Aizkraukles 21, LV-1006, Rıga, Latvia

    A. Plotniece & K. Pajuste

  3. UPMC University Paris 6 - PECSA UMR CNRS 7195, case 51, 4 place Jussieu, 75005, Paris, France

    G. Béalle, Ch. Ménager, E. Dubois & R. Perzynski

Authors
  1. O. Petrichenko
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  2. K. Ērglis
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  3. A. Cēbers
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  4. A. Plotniece
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  6. G. Béalle
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  8. E. Dubois
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  9. R. Perzynski
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Petrichenko, O., Ērglis, K., Cēbers, A. et al. Bilayer properties of giant magnetic liposomes formed by cationic pyridine amphiphile and probed by active deformation under magnetic forces. Eur. Phys. J. E 36, 9 (2013). https://doi.org/10.1140/epje/i2013-13009-0

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