Article Text

Download PDFPDF
Reminder of important clinical lesson
M pneumoniae infection, pulmonary thromboembolism and antiphospholipid antibodies
  1. Elia Ascer1,
  2. Marcus Marques2,
  3. Magnus Gidlund1
  1. 1Department of Immunology, University of Sao Paulo, Sao Paulo, Brazil
  2. 2Department of Biomedicine, Ciência e Sáude, Sao Paulo, Brazil
  1. Correspondence to Dr Elia Ascer, Elia.ascer{at}incor.usp.br

Summary

A 28-year-old, hypertensive and hypercholesterolaemic patient, was referred to our emergency unit with a mild thoracic pain, productive cough and a body temperature of 37.3°C. Laboratory examinations showed normal white cell count and moderate elevation of C reactive protein (CRP). Later, the thoracic pain increased accompanied by shortness of breath. High D-dimer was detected. Positive lupic anticoagulant factor and anticardiolipin and antibodies anti-Mycoplasma pneumoniae were present and high titres of antinuclear factor. Recombinant tissue-type plasminogen activator plus heparin and vancomycin were administered due the high possibility of mycoplasma pneumonia associated with pulmonary thromboembolism. CRP increased to very high levels with very mild modification of white blood cells during the evolution. Thoracic tomography and pulmonary scintigraphy of the lungs confirmed the diagnosis. The patient responded well and he was discharged after 25 days medicated with hydroxychloroquine sulphate, warfarin and aspirin. At present date he is well (150 days).

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Competing interests None.

  • Patient consent Obtained.