You are here

Article Text

Article menu
Download PDFPDF
PostScript
Letters
PDA and pulmonary hypertension: should the duct be ligated?
  1. V A McCulloch,
  2. R M Tulloh
  1. Department of Congenital Heart Disease, Bristol Royal Hospital for Children, Bristol, UK
  1. Correspondence to Robert Tulloh, Department of Congenital Heart Disease, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK; Robert.Tulloh{at}UHBristol.nhs.uk

https://doi.org/10.1136/adc.2009.161786

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Patency of the arterial duct (PDA) in preterm infants is associated with myocardial dysfunction, risk of chronic lung disease (CLD), pulmonary haemorrhage,1 intraventricular haemorrhage (IVH), necrotising enterocolitis (NEC), renal insufficiency and retinopathy of prematurity (ROP),2 and non-steroidal therapy has significant risks.3 Surgical ligation is considered in those with contraindications or who fail to respond to medical treatment. Some do well and are rapidly extubated, but mortality after ligation is 20% with an incidence of CLD of 77%, IVH 33%, NEC 26% and ROP 28%.2 4

    One hundred and seventy-three consecutive …

    View Full Text

    Footnotes

    • Competing interests None.

    • Provenance and Peer review Not commissioned; externally peer reviewed.

    • Ethics approval The study was approved as a service evaluation by our NHS trust.