Abstract
Seasonal changes in proteolytic activity and content of calpains in striated muscles of the longtailed ground squirrel Spermophilus undulatus were studied by casein zymography and Western blotting analysis. The results testify to hyperactivation of calpain proteases in the skeletal muscles of awakened animals during the “winter” activity. The observed changes are discussed in the context of adaptation of skeletal muscles of long-tailed ground squirrels to hibernation.
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Original Russian Text © S.S. Popova, I.M. Vikhlyantsev, N.M. Zakharova, Z.A. Podlubnaya, E.E. Fesenko, 2017, published in Doklady Akademii Nauk, 2017, Vol. 472, No. 4, pp. 487–490.
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Popova, S.S., Vikhlyantsev, I.M., Zakharova, N.M. et al. Seasonal changes in proteolytic activity of calpains in striated muscles of long-tailed ground squirrel Spermophilus undulatus . Dokl Biochem Biophys 472, 56–59 (2017). https://doi.org/10.1134/S1607672917010148
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DOI: https://doi.org/10.1134/S1607672917010148