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A potentiometric investigation of complex formation between some metal ions and biologically active quinazoline-4-3(H)-one Schiff’s base

  • Biophysical Chemistry
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Abstract

The proton dissociation constant of the ligand and the stability of the complexes of Co(II), Ni(II), Zn(II), Cd(II), Hg(II), Pb(II), Cu(II), Ba(II), Mg(II), Mn(II), Th(IV), and UO2(II) ions with 2-phenyl-3-(2′-hydroxy-5′-benzylidine)-quinazoline-4-(3H)-one [PBQ] were determined potentiometrically at 30 ± 0.1°C and ionic strengths of 0.025, 0.05, 0.10, 0.15 and 0.20 M NaNO3 in a 60:40 (v/v) ethanol-water medium. The proton-ligand and metal-ligand stability constants of the complexes were determined pH metrically by the Calvin-Bjerrum titration technique. The order of stability constants obeys the Irving-Rossotti rule. The negative values of ΔG° suggest that the reactions are spontaneous.

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Authors and Affiliations

  1. Department of Chemistry, Gulbarga University, India

    K. Shivakumar & M. B. Halli

  2. Materials Research Center, Indian Institute of Science, Bangalore, India

    S. Shashidhar

Authors
  1. K. Shivakumar
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  2. S. Shashidhar
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  3. M. B. Halli
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Correspondence to M. B. Halli.

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Shivakumar, K., Shashidhar, S. & Halli, M.B. A potentiometric investigation of complex formation between some metal ions and biologically active quinazoline-4-3(H)-one Schiff’s base. Russ. J. Phys. Chem. 81, 1681–1687 (2007). https://doi.org/10.1134/S0036024407100251

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  • DOI: https://doi.org/10.1134/S0036024407100251

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