Skip to main content
SpringerLink
Log in

The First Row Transition Metals on Stabilization of Biliverdin Complexes: Theoretical Study

  • THEORETICAL INORGANIC CHEMISTRY
  • Published:
Russian Journal of Inorganic Chemistry Aims and scope Submit manuscript

Abstract—

Biliverdin is a product of heme catabolism. It is the pigment responsible for a greenish color sometimes seen in bruises. Biliverdin has been found in excess in the blood of humans suffering from hepatic diseases. Structure of biliverdin from catabolism process of heme is one of the cases that has been less discussed. In this research characterization of biliverdin analogues in the presence of hydroxide as a nucleophile and imidazole as axial ligands was investigated using the B3LYP method and the 6-31G basis set both in gas and solvent phases. By changing the central metal in the structure of billiverdin, some features such as gap energy, hardness and softness, electrophilicicity index and exact polarizability were studied and compared with iron.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Fig. 7.
Fig. 8.

Similar content being viewed by others

REFERENCES

  1. P. R. Ortiz de Montellano and K. Auclair, in The Porphyrin Handbook, Vol. 12: Heme Oxygenase Structure and Function, Ed. by K. M. Kadish, K. M. Smith, and R. Guilard (Elsevier, New York, 2003), p. 183.

  2. M. D. Bissell and Imliver, in Normal Function and Disease, Vol. 4: Bile Pigments and Jaundice, Ed. by J. D. Ostrow (Marcel Decker, New York, 1986).

  3. L. Mosqueda, K. Burnight, and S. Liao, J. Am. Geram. Soc. 53, 1339 (2005). https://doi.org/10.1111/j.1532-5415.2005.53406.x

    Article  Google Scholar 

  4. M. Unno, T. Matsui, and M. Ikeda-Saito, J. Inorg. Biochem., 113, 102 (2012). https://doi.org/10.1016/j.jinorgbio.2012.04.012

    Article  CAS  PubMed  Google Scholar 

  5. M. Sugishima, H. Sakamoto, Y. Higashimoto, et al., J. Biol. Chem. 278, 32352 (2003). https://doi.org/10.1074/jbc.M303682200

    Article  CAS  PubMed  Google Scholar 

  6. M. Unno, A. Ardèvol, C. Rovira, et al., J. Biol. Chem. 288, 34443 (2013). https://doi.org/10.1074/jbc.M113.486936

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. M. Gheidi, N. Safari, H. Bahrami, et al., J. Inorg. Biochem. 101, 385 (2007). https://doi.org/10.1016/j.jinorgbio.2006.10.012

    Article  CAS  PubMed  Google Scholar 

  8. H. Bahrami, N. Safari, and M. Zahedi, J. Inorg. Biochem. 100, 1449 (2006). .https://doi.org/10.1016/j.jinorgbio.2006.04.010

    Article  CAS  PubMed  Google Scholar 

  9. M.D. Davari, M, Zahedi, N. Safari, et al., J. Mol. Modeling. 15, 1299 (2009). https://doi.org/10.1007/s00894-009-0495-0

    Article  CAS  Google Scholar 

  10. A. Taghizadeh, M. Daghighi, and P. R Jamaat. J. Porphyrins Phthalocyanines. 23, 1 (2019). .https://doi.org/10.1142/S1088424619501311

    Article  CAS  Google Scholar 

  11. M. J. Frisch, G. W. Trucks, H. B. Schlegel et al., Gaussian 09, Revision A.02 (Gaussian, Wallingford CT, 2009).

    Google Scholar 

  12. R. G. Parr and W. Yang, Density Functional Theory of Atoms and Molecules (Oxford Univ. Press, Oxford, 1989).

    Google Scholar 

  13. C. J. Cramer, Essentials of Computational Chemistry: Theories and Models (Wiley, Chichester, 2002).

    Google Scholar 

  14. E. M. Siegbahn, Faraday Discuss. 124, 289 (2003). https://doi.org/10.1039/B211811B

    Article  CAS  PubMed  Google Scholar 

  15. L. Szterenberg, L. Latos-Grazynski, and J. Wojaczynski, ChemPhysChem 4, 691 (2003). https://doi.org/10.1002/cphc.200200611

    Article  CAS  PubMed  Google Scholar 

  16. G. I. Semushkina, L. N. Mazalov, S. A. Lavrukhina, et al., J. Struct. Chem. 61, 377 (2020). https://doi.org/10.1134/S0022476620030051

    Article  CAS  Google Scholar 

  17. O. P. Charkin, Russ. J. Inorg. Chem. 58, 300 (2013). https://doi.org/10.1134/S0036023613030042

    Article  CAS  Google Scholar 

  18. M. Khazri, K. Sahra, A. Milet, et al., J. Struct. Chem. 61, 844 (2020). https://doi.org/10.1134/S0022476620060025

    Article  CAS  Google Scholar 

  19. O. P. Charkin, A. V. Makarov, and N. M. Klimenko, Russ. J. Inorg. Chem. 53, 718 (2008). https://doi.org/10.1134/S0036023608050100

    Article  Google Scholar 

  20. Z. El Adnani, M. Mcharfi, M. Sfaira, et al., Struct. Chem. 31, 631 (2019). https://doi.org/10.1007/s11224-019-01435-5

    Article  CAS  Google Scholar 

  21. J. Tomasi, B. Mennucci, and R. Cammi, Chem. Rev. 105, 2999 (2005). https://doi.org/10.1021/cr9904009

    Article  CAS  PubMed  Google Scholar 

  22. P. R. Jamaat, N. Safari, M. Ghiasi, et al., J. Biol. Inorg. Chem. 13, 121 (2008).https://doi.org/10.1007/s00775-007-0308-9

    Article  CAS  PubMed  Google Scholar 

  23. Lu Wei., Yuanbin She., Yanmin Yu., et al., J. Mol. Model. 18, 2483(2012).https://doi.org/10.1007/s00894-011-1279-x

    Article  CAS  PubMed  Google Scholar 

  24. R. G. Pearson, Chemical Hardness (Wiley, Oxford, 1997).

    Book  Google Scholar 

  25. R. G. Parr and W. Yang., Density Functional Theory of Atoms and Molecules (Oxford Univ Press, New York, 1989).

    Google Scholar 

  26. R. G. Parr, L. v. Szentpály, S. Liu, J. Am. Chem. Soc. 121, 1922 (1999).https://doi.org/10.1021/ja983494x

    Article  CAS  Google Scholar 

Download references

ACKNOWLEDGMENTS

We are Thankful to Azad University of Tehran (central branch) for making available software and hardware (machine time) facilities to us and also thank the Research Council of Azad University of Tehran Markaz for support.

Author information

Authors and Affiliations

  1. Department of Chemistry, Central Tehran Branch, Islamic Azad University, Tehran, Iran

    A. Taghizadeh & Maryam Daghighi Asli

  2. Department of Chemistry, East Tehran Branch, Islamic Azad University, Tehran, Iran

    Parisa Rajabali Jamaat

Authors
  1. A. Taghizadeh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Parisa Rajabali Jamaat
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Maryam Daghighi Asli
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Parisa Rajabali Jamaat.

Ethics declarations

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Taghizadeh, A., Jamaat, P.R. & Asli, M.D. The First Row Transition Metals on Stabilization of Biliverdin Complexes: Theoretical Study. Russ. J. Inorg. Chem. 66, 516–524 (2021). https://doi.org/10.1134/S0036023621040227

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0036023621040227

Keywords:

Search

Navigation