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Synthesis of conformationally restricted Analogs of γ-aminobutyric acid

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Abstract

Data on methods of the synthesis of conformationally restricted analogs of γ-aminobutyric acid (GABA) are systematized in the review. Approaches to the synthesis of different types of conformationally restricted GABA analogs are presented: γ-aminobutenoic acids, aminocycloalkanecarboxylic acids, carboxy-substituted azetidines, prolines, amino acids containing aromatic (heterocyclic including) fragments.

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Correspondence to N. V. Yashin.

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Original Russian Text © N.V. Yashin, T.N. Chmovzh, E.B. Averina, T.S. Kuznetsova, N.S. Zefirov, 2014, published in Obzornyi Zhurnal po Khimii, 2014, Vol. 4, No. 4, pp. 149–168.

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Yashin, N.V., Chmovzh, T.N., Averina, E.B. et al. Synthesis of conformationally restricted Analogs of γ-aminobutyric acid. Ref. J. Chem. 4, 253–275 (2014). https://doi.org/10.1134/S2079978014040049

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  • DOI: https://doi.org/10.1134/S2079978014040049

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