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The radioprotective and prophylactic properties of biologically active substances prepared by supercritical fluid extraction from pine shoots

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Abstract

The radioprotective properties of a substance from pine shoots prepared by supercritical fluid extraction with carbon dioxide were studied for a model of an experimental bone-marrow radiation sickness form. Experiments were performed for white nonlinear mice. The CO2 extract of pine shoots was shown to possess radioprotective properties. The extract was subjected to pre-clinical tests for Wistar line male rats with respect to its antiatherogenic and antioxidative action in the creation of experimental hyperlipemia.

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Authors and Affiliations

  1. Research Institute of Chemistry, Nizhni Novgorod State University, pr. Gagarina 23/5, Nizhni Novgorod, Russia

    V. F. Ur’yash & N. Yu. Kokurina

  2. OOO “Grande”, Nizhni Novgorod, Russia

    A. E. Gruzdeva

  3. Mount Sinai Medical Center, Miami Beach, Florida, USA

    A. V. Ur’yash

  4. Nizhni Novgorod State University, pr. Gagarina 23, Nizhni Novgorod, Russia

    A. A. Silkin

Authors
  1. V. F. Ur’yash
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  2. A. E. Gruzdeva
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  3. A. V. Ur’yash
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  4. A. A. Silkin
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  5. N. Yu. Kokurina
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Corresponding author

Correspondence to V. F. Ur’yash.

Additional information

Original Russian Text © V.F. Ur’yash, A.E. Gruzdeva, A.V. Ur’yash, A.A. Silkin, N.Yu. Kokurina, 2010, published in Sverkhkriticheskie Flyuidy: Teoriya i Praktika, 2010, Vol. 5, No. 1, pp. 79–87.

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Ur’yash, V.F., Gruzdeva, A.E., Ur’yash, A.V. et al. The radioprotective and prophylactic properties of biologically active substances prepared by supercritical fluid extraction from pine shoots. Russ. J. Phys. Chem. B 4, 1097–1102 (2010). https://doi.org/10.1134/S1990793110070080

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  • DOI: https://doi.org/10.1134/S1990793110070080

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