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Synthesis of 4-Halo-3-isopropoxyfuro[3,4-с]-pyridin-1(3H)-ones

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Abstract

The reaction of 4-halo-3-hydroxyfuro[3,4-c]pyridin-1(3H)-ones with propan-2-ol leads to the formation of 4-halo-3-isopropoxyfuro[3,4-c]pyridin-1(3H)-ones. The reaction takes place in the presence of sulfuric acid and 3 Å molecular sieves.

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Funding

The work was funded by a grant from the President of the Russian Federation for state support of young Russian scientists (no. MK-5982.2018.3).

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Authors and Affiliations

  1. Ul’yanov Chuvash State University, Moskovskii pr. 15, Cheboksary, Chuvash Republic, 428015, Russia

    S. V. Fedoseev, K. V. Lipin & M. Yu. Belikov

  2. Lomonosov Moscow State University, Leninskie gory 1, str. 3, Moscow, 119991, Russia

    V. A. Tafeenko

Authors
  1. S. V. Fedoseev
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  2. K. V. Lipin
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  3. M. Yu. Belikov
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  4. V. A. Tafeenko
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Correspondence to S. V. Fedoseev.

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Russian Text © The Author(s), 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 11, pp. 1689–1694.

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Fedoseev, S.V., Lipin, K.V., Belikov, M.Y. et al. Synthesis of 4-Halo-3-isopropoxyfuro[3,4-с]-pyridin-1(3H)-ones. Russ J Org Chem 55, 1669–1673 (2019). https://doi.org/10.1134/S1070428019110046

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  • DOI: https://doi.org/10.1134/S1070428019110046

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