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Synthesis of Polyfunctionalized Hexahydropyrimidines

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Abstract

The reactions of alkyl 5-acetylhexahydropyrimidine-5-carboxylates with ammonia, hydrazine hydrate, and lithium aluminum hydride were used to synthesize hexahydropyrimidine derivatives containing pharmacophoric 1,3-propylenediamine and 1,3-propanolamine fragments.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Research Center, Russian Academy of Sciences, pr. Oktyabrya 69, Ufa, 450054, Russia

    A. G. Badamshin, D. R. Latypova & V. A. Dokichev

  2. Ufa State Aviation Technical University, ul. K. Marksa 12, Ufa, 450008, Russia

    A. G. Badamshin & V. A. Dokichev

Authors
  1. A. G. Badamshin
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  2. D. R. Latypova
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  3. V. A. Dokichev
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Corresponding author

Correspondence to V. A. Dokichev.

Additional information

Russian Text © A.G. Badamshin, D.R. Latypova, V.A. Dokichev, 2019, published in Zhurnal Organicheskoi Khimii, 2019, Vol. 55, No. 2, pp. 215–220.

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Badamshin, A.G., Latypova, D.R. & Dokichev, V.A. Synthesis of Polyfunctionalized Hexahydropyrimidines. Russ J Org Chem 55, 168–173 (2019). https://doi.org/10.1134/S1070428019020076

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  • DOI: https://doi.org/10.1134/S1070428019020076

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