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α-Amino azoles in the synthesis of heterocycles: VI. Synthesis and structure of cycloalkane-annulated pyrazolo[1,5-a]pyrimidines

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Abstract

Reactions of 4-aryl-1H-pyrazol-5(3)-amines with 2-acylcycloakanones and 2-acyl-5,5-dimethylcyclohexane-1,3-diones led to the formation of regioisomeric 6,7,8,9-tetrahydropyrazolo[1,5-a]quinazoline, 5,6,7,8-tetrahydropyrazolo[5,1-b]quinazoline, and 7,8-dihydro-6H-cyclopenta[e]pyrazolo[1,5-a]pyrimidine derivatives. The product structure was determined by X-ray analysis and 1H and 13C NMR spectroscopy.

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Authors and Affiliations

  1. St. Petersburg State University, Universitetskii pr. 26, St. Petersburg, 198504, Russia

    A. A. Petrov, A. N. Kasatochkin & E. E. Emelina

  2. Nesmeyanov Institute of Organometallic Compounds, Russian Academy of Sciences, ul. Vavilova 28, Moscow, 119991, Russia

    Yu. V. Nelyubina & M. Yu. Antipin

Authors
  1. A. A. Petrov
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  2. A. N. Kasatochkin
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  3. E. E. Emelina
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  4. Yu. V. Nelyubina
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  5. M. Yu. Antipin
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Correspondence to A. A. Petrov.

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Original Russian Text © A.A. Petrov, A.N. Kasatochkin, E.E. Emelina, Yu.V. Nelyubina, M.Yu. Antipin, 2009, published in Zhurnal Organicheskoi Khimii, 2009, Vol. 45, No. 9, pp. 1403–1414.

For communication V, see [1].

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Petrov, A.A., Kasatochkin, A.N., Emelina, E.E. et al. α-Amino azoles in the synthesis of heterocycles: VI. Synthesis and structure of cycloalkane-annulated pyrazolo[1,5-a]pyrimidines. Russ J Org Chem 45, 1390–1401 (2009). https://doi.org/10.1134/S1070428009090139

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  • DOI: https://doi.org/10.1134/S1070428009090139

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