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Synthesis of nitriles containing 3-phenoxyphenyl fragment

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Abstract

Reactions of the aldol-crotonic condensation, acylation of acetonitrile, and addition of amine to the activated double bond of acrylonitrile in the series of diphenyl oxide derivatives are studied. Effective procedures for preparing the nitriles containing diphenyl oxide fragment like 3-(3-phenoxyphenyl)-propenonitrile, 3-(3-phenoxyphenyl)-2-butenonitrile, 3-phenoxybenzoylacetonitrile, 3-(3-phenoxyphenyl)-propionitrile, and 3-phenoxybenzylamino)propionitrile are developed.

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Correspondence to V. S. Kamaletdinova.

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Original Russian Text © Yu.V. Popov, T.G. Korchagina, V.S. Kamaletdinova, 2010, published in Zhurnal Obshchei Khimii, 2010, Vol. 80, No. 4, pp. 614–618.

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Popov, Y.V., Korchagina, T.G. & Kamaletdinova, V.S. Synthesis of nitriles containing 3-phenoxyphenyl fragment. Russ J Gen Chem 80, 776–780 (2010). https://doi.org/10.1134/S107036321004016X

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  • DOI: https://doi.org/10.1134/S107036321004016X

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