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Initial steps of dissolution of monoclinic and rhombic crystals of paracetamol

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Abstract

The initial steps of dissolution of Paracetamol (monoclinic and rhombic modifications) in a series of solvents (10% solutions of acetic anhydride, pyridine, 1,4-dioxane, morpholine, and N-methylmorpholine in CCl4) were studied. The etching patterns on planes parallel and perpendicular to Paracetamol molecular layers were compared.

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Authors and Affiliations

  1. Novosibirsk State University, ul. Pirogova 2, Novosibirsk, 630090, Russia

    M. A. Mikhailenko, T. N. Drebushchak & V. V. Boldyrev

  2. Research and Education Center of Molecular Design and Environmentally Safe Technologies, Novosibirsk State University, Novosibirsk, Russia

    M. A. Mikhailenko, T. P. Shakhtshneider, T. N. Drebushchak & V. V. Boldyrev

  3. Institute of Solid State Chemistry and Mechanochemistry, Siberian Division, Russian Academy of Sciences, Novosibirsk, Russia

    T. P. Shakhtshneider, T. N. Drebushchak & V. V. Boldyrev

Authors
  1. M. A. Mikhailenko
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  2. T. P. Shakhtshneider
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  3. T. N. Drebushchak
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  4. V. V. Boldyrev
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Additional information

Original Russian Text © M.A. Mikhailenko, T.P. Shakhtshneider, T.N. Drebushchak, V.V. Boldyrev, 2006, published in Zhurnal Obshchei Khimii, 2006, Vol. 76, No. 1, pp. 52–59.

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Mikhailenko, M.A., Shakhtshneider, T.P., Drebushchak, T.N. et al. Initial steps of dissolution of monoclinic and rhombic crystals of paracetamol. Russ J Gen Chem 76, 48–54 (2006). https://doi.org/10.1134/S1070363206010117

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  • DOI: https://doi.org/10.1134/S1070363206010117

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