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Fish Growth Hormone Genes: Structure and Divergence

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Abstract

This review provides information on the structure of growth hormone genes (GHGs) in fish and the divergence of coding, intron, and adjacent flanking regions; original data obtained in our laboratory are also considered. In most fish species, GHGs are represented by a single copy, while some taxonomic groups have two paralogous genes. The coding sequences of GHGs are conserved. Gene length variations depend on the length of non-coding and flanking regions and introns. The divergence rate of gene sequences varies not only between different taxonomic groups, but also in the time of divergence within groups. In flanking regions, only the regulatory elements are conserved.

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REFERENCES

  1. Kamenskaya, D.N., Pankova, M.V., Atopkin, D.M., and Brykov, V.A., Fish growth-hormone genes: Evidence of functionality of paralogous genes in Levanidov’s charr Salvelinus levanidovi,Mol. Biol. (Moscow), 2015, vol. 49, no. 5, pp. 687–693.

    Article  CAS  Google Scholar 

  2. Kamenskaya, D.N., Pankova, M.V., Atopkin, D.M., and Brykov, V.A., Divergence of paralogous growth-hormone-encoding genes and their promoters in Salmonidae, Mol. Biol. (Moscow), 2017, vol. 51, no. 2, pp. 274–282.

    Article  CAS  Google Scholar 

  3. Pankova, M.V., Brykov, Vl.A., Pankova, V.V., and Atopkin, D.M., Fish growth hormone genes: Divergence of intron sequence in charrs of Salvelinus genus, Russ. J. Genet., 2013, vol. 49, no. 6, pp. 645–651.

    Article  CAS  Google Scholar 

  4. Pankova, M.V., Kukhlevsky, A.D., and Brykov, V.A., Fish growth hormone genes: Divergence of coding sequences in salmonid fishes, Russ. J. Genet., 2017, vol. 53, no. 2, pp. 221–232.

    Article  CAS  Google Scholar 

  5. Agellon, L.B. and Chen, T.T., Rainbow trout growth hormone: molecular cloning of cDNA and expression in Escherichia coli,DNA, 1986, vol. 5, no. 6, pp. 463–471.

    Article  CAS  PubMed  Google Scholar 

  6. Agellon, L.B., Davies, S.L., Chen, T.T., and Powers, D.A., Structure of a fish (rainbow trout) growth hormone gene and its evolutionary implications, Proc. Natl. Acad. Sci. U. S. A., 1988, vol. 85, no. 14, pp. 5136–5140.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Allendorf, F.W. and Thorgaard, G.H., Tetraploidy and the evolution of salmonid fishes, in Evolutionary Biology of Fishes, New York: Plenum, 1984, pp. 1–53.

    Google Scholar 

  8. Almuly, R., Cavari, B., Ferstman, H., et al., Genomic structure and sequence of the gilthead seabream (Sparus aurata) growth hormone-encoding gene: Identification of minisatellite polymorphism in intron I, Genome, 2000, vol. 43, no. 5, pp. 836–845.

    Article  CAS  PubMed  Google Scholar 

  9. Almuly, R., Poleg-Danin, Y., Gorshkov, S., et al., Characterization of the 5' flanking region of the growth hormone gene of the marine teleost, gilthead sea bream Sparus aurata: analysis of a polymorphic microsatellite in the proximal promoter, Fish. Sci., 2005, vol. 71, no. 3, pp. 479–490.

    Article  CAS  Google Scholar 

  10. Arai, N. and Iigo, M., Duplicated growth hormone genes in a passerine bird, the jungle crow (Corvus macrorhynchos), Biochem. Biophys. Res. Commun., 2010, vol. 397, no. 3, pp. 553–558.

    Article  CAS  PubMed  Google Scholar 

  11. Argenton, F., Bernardini, S., Puttini, S., et al., A TGACG motif mediates growth-hormone-factor-l/pituitary-transcriptional-activator-1-dependent cAMP regulation of the rainbow trout growth-hormone promoter, Eur. J. Biochem., 1996, vol. 238, no. 3, pp. 591–598.

    Article  CAS  PubMed  Google Scholar 

  12. Argenton, F., Vianello, S., Bernardini, S., et al., Trout GH promoter analysis reveals a modular pattern of regulation consistent with the diversification of GH gene control and function in vertebrates, Mol. Cell. Endocrinol., 2002, vol. 189, nos. 1–2, pp. 11–23.

    Article  CAS  PubMed  Google Scholar 

  13. Barnett, K.R., Hopkins, R.L., and Peyton, D.K., A minisatellite in the growth hormone gene of Esocidae is derived from a single copy element in the salmonid genome, Copeia, 2007, vol. 2007, no. 1, pp. 205–211.

    Article  Google Scholar 

  14. Barrera-Saldaña, H.A., Growth hormone and placental lactogen: biology, medicine and biotechnology, Gene, 1998, vol. 211, no. 1, pp. 11–18.

  15. Bart, H.L., Jr., Reneau, P.C., Doosey, M.H., and Bell, C.B., Evolutionary divergence of duplicate copies of the growth hormone gene in suckers (Actinopterygii: Catostomidae), Int. J. Mol. Sci., 2010, vol. 11, no. 3, pp. 1090–1102.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Barta, A., Richards, R.I., Baxter, J.D., and Shine, J., Primary structure and evolution of rat growth hormone gene, Proc. Natl. Acad. Sci. U. S. A., 1981, vol. 78, no. 8, pp. 4867–4871.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Beato, M., Chalepakis, G., Schauer, M., and Slater, E.P., DNA regulatory elements for steroid hormones, J. Steroid Biochem., 1989, vol. 32, no. 5, pp. 737–748.

    Article  CAS  PubMed  Google Scholar 

  18. Ber, R. and Daniel, V., Structure and sequence of the growth hormone-encoding gene from Tilapia nilotica,Gene, 1992, vol. 113, no. 2, pp. 245–250.

    Article  CAS  PubMed  Google Scholar 

  19. Bernardini, S., Argenton, F., Vianello, S., et al., Regulatory regions in the promoter and third intron of the growth hormone gene in rainbow trout, Oncorhynchus mykiss Walbaum, Gen. Comp. Endocrinol., 1999, vol. 116, no. 2, pp. 261–271.

    Article  CAS  PubMed  Google Scholar 

  20. Blomhoff, R. and Blomhoff, H.K., Overview of retinoid metabolism and function, J. Neurobiol., 2006, vol. 66, no. 7, pp. 606–630.

    Article  CAS  PubMed  Google Scholar 

  21. Buggiotti, L., Hellström, M.A., and Primmer, C.R., Characterization of the first growth hormone gene sequence for a passerine bird—the pied flycatcher (Ficedula hypoleuca), DNA Sequence, 2006, vol. 17, no. 6, pp. 401–406.

    Article  CAS  PubMed  Google Scholar 

  22. Buggiotti, L. and Primmer, C.R., Molecular evolution of the avian growth hormone gene and comparison with its mammalian counterpart, J. Evol. Biol., 2006, vol. 19, no. 3, pp. 844–854.

    Article  CAS  PubMed  Google Scholar 

  23. Chen, E.Y., Liao, Y.-C, Smith, D.H., et al., The human growth hormone locus: Nucleotide sequence, biology, and evolution, Genomics, 1989, vol. 4, no. 4, pp. 479–497.

    Article  CAS  PubMed  Google Scholar 

  24. Chen, T.T., Agellon, L.B., Lin, C.M., et al., Evolutionary implications of two rainbow trout growth hormone genes, Fish Physiol. Biochem., 1989, vol. 7, art. ID 381. https://doi.org/10.1007/BF00004732

    Article  CAS  PubMed  Google Scholar 

  25. Chiou, C.-S., Chen, H.T., and Chang, W.C., The complete nucleotide sequence of the growth-hormone gene from the common carp (Cyprinus carpio), Biochim. Biophys. Acta,Gene Struct. Expression, 1990, vol. 1087, no. 1, pp. 91–94.

    Article  CAS  Google Scholar 

  26. Das, P., Meyer, L., Seyfert, H.-M., et al., Structure of the growth hormone-encoding gene and its promoter in mice, Gene, 1996, vol. 169, no. 2, pp. 209–213.

    Article  CAS  PubMed  Google Scholar 

  27. Daza, D.O. and Larhammar, D., Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family, Gen. Comp. Endocrinol., 2018, vol. 264, pp. 94–112.

    Article  CAS  Google Scholar 

  28. Deng, S.-P., Wu, B., Zhu, C.-H., and Li, G.-L., Molecular cloning and dimorphic expression of growth hormone (gh) in female and male spotted scat Scatophagus argus,Fish. Sci., 2014, vol. 80, no. 4, pp. 715–723.

    Article  CAS  Google Scholar 

  29. DeNoto, F.M., Moore, D.D., and Goodman, H.M., Human growth hormone DNA sequence and mRNA structure: possible alternative splicing, Nucleic Acids Res., 1981, vol. 9, no. 15, pp. 3719–3730.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Devlin, R.H., Sequence of sockeye salmon type 1 and 2 growth hormone genes and the relationship of rainbow trout with Atlantic and Pacific salmon, Can. J. Fish. Aquat. Sci., 1993, vol. 50, no. 8, pp. 1738–1748.

    Article  CAS  Google Scholar 

  31. Du, S.J., Devlin, R.H., and Hew, C.L., Genomic structure of growth hormone genes in chinook salmon (Oncorhynchus tshawytscha): presence of two functional genes, GH-I and GH-II, and a male-specific pseudogene, GH-ψ, DNA Cell Biol., 1993, vol. 12, no. 8, pp. 739–751.

    Article  CAS  PubMed  Google Scholar 

  32. Farchi-Pisanty, O., Sternberg, H., and Moav, B., Transcriptional regulation of fish growth hormone gene, Fish Physiol. Biochem., 1997, vol. 17, pp. 237–246.

    Article  CAS  Google Scholar 

  33. Forbes, S.H., Knudsen, K.L., North, T.W., and Allendorf, F.W., One of two growth hormone genes in coho salmon is sex-linked, Proc. Natl. Acad. Sci. U. S. A., 1994, vol. 91, no. 5, pp. 1628–1631.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  34. González-Alvarez, R., Revol de Mendoza, A., Esquivel Escobedo, D., et al., Growth hormone locus expands and diverges after the separation of New and Old World monkeys, Gene, 2006, vol. 380, no. 1, pp. 38–45.

  35. Gordon, D.F., Quick, D.P., Erwin, C.R., et al., Nucleotide sequence of the bovine growth hormone chromosomal gene, Mol. Cell. Endocrinol., 1983, vol. 33, no. 1, pp. 81–95.

    Article  CAS  PubMed  Google Scholar 

  36. Hirt, H., Kimelman, J., Birnbaum, M.J., et al., The human growth hormone gene locus: structure, evolution and allelic variations, DNA, 1987, vol. 6, no. 1, pp. 59–70.

    Article  CAS  PubMed  Google Scholar 

  37. Holland, L.Z., Albalat, R., Azumi, K., et al., The amphioxus genome illuminates vertebrate origins and cephalochordate biology, Genome Res., 2008, vol. 18, no. 7, pp. 1100–1111.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Hong, Y. and Schartl, M., Sequence of the growth hormone (GH) gene from the silver carp (Hypophthalmichthys molitrix) and evolution of the GH genes in vertebrates, Biochim. Biophysi Acta,Gene Struct. Expression, 1993, vol. 1174, no. 3, pp. 285–288.

    Article  CAS  Google Scholar 

  39. Houston, R.D. and Macqueen, D.J., Atlantic salmon (Salmo salar L.) genetics in the 21st century: taking leaps forward in aquaculture and biological understanding, Anim. Genet., 2019, vol. 50, no. 1, pp. 3−14.

    Article  CAS  PubMed  Google Scholar 

  40. Johansen, B., Johnsen, O.C., and Valla, S., The complete nucleotide sequence of the growth-hormone gene from Atlantic salmon (Salmo salar), Gene, 1989, vol. 77, no. 2, pp. 317–324.

    Article  CAS  PubMed  Google Scholar 

  41. Jones, B.K., Monks, B.R., Liebhaber, S.A., and Cooke, N.E., The human growth hormone gene is regulated by a multicomponent locus control region, Mol. Cell. Biol., 1995, vol. 15, no. 12, pp. 7010–7021.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  42. Kansaku, N., Soma, A., Furukawa, S., et al., Sequence of the domestic duck (Anas platyrhynchos) growth hormone-encoding gene and genetic variation in the promoter region, Anim. Sci. J., 2008, vol. 79, no. 2, pp. 163–170.

    Article  CAS  Google Scholar 

  43. Kawauchi, H., Moriyama, S., Yasuda, A., et al., Isolation and characterization of chum salmon growth hormone, Arch. Biochem. Biophys., 1986, vol. 244, no. 2, pp. 542–552.

    Article  CAS  PubMed  Google Scholar 

  44. Kawauchi, H., Suzuki, K., Yamazaki, T., et al., Identification of growth hormone in the sea lamprey, an extant representative of a group of the most ancient vertebrates, Endocrinology, 2002, vol. 143, no. 12, pp. 4916–4921.

    Article  CAS  PubMed  Google Scholar 

  45. Kliewer, S.A., Umesono, K., Heyman, R.A., et al., Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling, Proc. Natl. Acad. Sci. U. S. A., 1992, vol. 89, no. 4, pp. 1448–1452.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Kobayashi, T., Yasuda, A., Yamaguchi, K., et al., The complete amino acid sequence of growth hormone of the bullfrog (Rana catesbeiana), Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol., vol. 1078, no. 3, pp. 383–387.

  47. Li, M., Gao, Z., Ji, D., and Zhang, S., Functional characterization of GH-like homolog in amphioxus reveals an ancient origin of GH/GH receptor system, Endocrinology, 2014, vol. 155, no. 12, pp. 4818–4830.

    Article  PubMed  CAS  Google Scholar 

  48. Lioupis, A., Wallis, O.C., and Wallis, M., Cloning and characterisation of the gene encoding red deer (Cervus elaphus) growth hormone: implications for the molecular evolution of growth hormone in artiodactyls, J. Mol. Endocrinol., 1997, vol. 19, no. 3, pp. 259–266.

    Article  CAS  PubMed  Google Scholar 

  49. Lioupis, A., Nevo, E., and Wallis, M., Cloning and characterisation of the gene encoding mole rat (Spalax ehrenbergi) growth hormone, J. Mol. Endocrinol., 1999, vol. 22, no. 1, pp. 29–36.

    Article  CAS  PubMed  Google Scholar 

  50. Male, R., Nerland, A.N., Lorens, J.B., et al., The complete nucleotide sequence of the Atlantic salmon growth hormone I gene, Biochim. Biophys. Acta,Gene Struct. Expression, 1992, vol. 1130, no. 3, pp. 345–348.

    Article  CAS  Google Scholar 

  51. Maniou, Z., Wallis, O.C., and Wallis, M., Episodic molecular evolution of pituitary growth hormone in Cetartiodactyla, J. Mol. Evol., 2004, vol. 58, no. 6, pp. 743–753.

    Article  CAS  PubMed  Google Scholar 

  52. McKay, S.J., Devlin, R.H., and Smith, M.J., Phylogeny of Pacific salmon and trout based on growth hormone type-2 and mitochondrial NADH dehydrogenase subunit 3 DNA sequences, Can. J. Fish. Aquat. Sci., 1996, vol. 53, no. 5, pp. 1165–1176.

    Article  CAS  Google Scholar 

  53. Moriyama, S., Oda, M., Takahashi, A., et al., Genomic structure of the sea lamprey growth hormone-encoding gene, Gen. Comp. Endocrinol., 2006, vol. 148, no. 1, pp. 33–40.

    Article  CAS  PubMed  Google Scholar 

  54. Moriyama, S., Oda, M., Yamazaki, T., et al., Gene structure and functional characterization of growth hormone in dogfish, Squalus acanthias,Zool. Sci., 2008, vol. 25, no. 6, pp. 604–613.

    Article  CAS  Google Scholar 

  55. Noso, T., Lance, V.A., and Kawauchi, H., Complete amino acid sequence of crocodile growth hormone, Gen. Comp. Endocrinol., 1995, vol. 98, no. 3, pp. 244–252.

    Article  CAS  PubMed  Google Scholar 

  56. Oakley, T.H. and Phillips, R.B., Phylogeny of salmonine fishes based on growth hormone introns: Atlantic (Salmo) and Pacific (Oncorhynchus) salmon are not sister taxa, Mol. Phylogenet. Evol., 1999, vol. 11, no. 3, pp. 381–393.

    Article  CAS  PubMed  Google Scholar 

  57. Ohkubo, T., Araki, M., Tanaka, M., et al., Molecular cloning and characterization of the yellowtail GH gene and its promoter: a consensus sequence for teleost and avian Pit-1/GHF-1 binding sites, J. Mol. Endocrinol., 1996, vol. 16, no. 1, pp. 63–72.

    Article  CAS  PubMed  Google Scholar 

  58. Panicz, R., Sadowski, J., and Drozd, R., Genetic and structural characterization of the growth hormone gene and protein from tench, Tinca tinca,Fish Physiol. Biochem., 2012, vol. 38, no. 6, pp. 1645–1653.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Pérez-Maya, A.A., Wallis, M., and Barrera-Saldaña, H.A., Structure and evolution of the gorilla and orangutan growth hormone loci, Mamm. Genome, 2016, vol. 27, nos. 9–10, pp. 511–523.

  60. Phillips, R.B., Matsuoka, M.P., Konkol, N.R., and McKay, S., Molecular systematics and evolution of the growth hormone introns in the Salmoninae, Environ. Biol. Fishes, 2004, vol. 69, nos. 1–4, pp. 433–440.

    Article  Google Scholar 

  61. Rajesh, R. and Majumdar, K.C., A comparative account of the structure of the growth hormone encoding gene and genetic interrelationship in six species of the genus Labeo,Fish Physiol. Biochem., 2007, vol. 33, no. 4, art. ID 311. https://doi.org/10.1007/s10695-007-9164-3

    Article  CAS  Google Scholar 

  62. Rodríguez-Sánchez, I.P., Tejero, M.E., Cole, S.A., et al., Growth hormone-related genes from baboon (Papio hamadryas): characterization, placental expression and evolutionary aspects, Gene, 2010, vol. 450, nos. 1–2, pp. 1–7.

  63. Ryynänen, H.J. and Primmer, C.R., Varying signals of the effects of natural selection during teleost growth hormone gene evolution, Genome, 2006, vol. 49, no. 1, pp. 42–53.

  64. Saunders, M.C., Deakin, J., Harrison, G.A., and Curlewis, J.D., cDNA cloning of growth hormone from the brushtail possum (Trichosurus vulpecula), Gen. Comp. Endocrinol., 1998, vol. 111, no. 1, pp. 68–75.

    Article  CAS  PubMed  Google Scholar 

  65. Sekar, M., Singh, S.D., and Gupta, S., Cloning and characterization of Pangasianodon hypophthalmus growth hormone gene and its heterologous expression, Appl. Biochem. Biotechnol., 2014, vol. 173, pp. 1446–1468.

    Article  CAS  PubMed  Google Scholar 

  66. Sekkali, B., Brim, H., Muller, M., et al., Structure and functional analysis of a tilapia (Oreochromis mossambicus) growth hormone gene: activation and repression by pituitary transcription factor Pit-1, DNA Cell Biol., 1999, vol. 18, no. 6, pp. 489–502.

    Article  CAS  PubMed  Google Scholar 

  67. Sternberg, H. and Moav, B., Regulation of the growth hormone gene by fish thyroid/retinoid receptors, Fish Physiol. Biochem., 1999, vol. 20, no. 4, pp. 331–339.

    Article  CAS  Google Scholar 

  68. Su, Y., Liebhaber, S.A., and Cooke, N.E., The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse, J. Biol. Chem., 2000, vol. 275, no. 11, pp. 7902–7909.

    Article  CAS  PubMed  Google Scholar 

  69. Tanaka, M., Hosokawa, Y., Watahiki, M., and Nakashima, K., Structure of the chicken growth hormone-encoding gene and its promoter region, Gene, 1992, vol. 112, no. 2, pp. 235–239.

    Article  CAS  PubMed  Google Scholar 

  70. Tanaka, M., Toma, Y., Ohkubo, T., et al., Sequence of the flounder (Paralichthys olivaceus) growth hormone-encoding gene and its promoter region, Gene, 1995, vol. 165, no. 2, pp. 321–322.

    Article  CAS  PubMed  Google Scholar 

  71. Valinsky, A., Shani, M., and Gootwine, E., Restriction fragment length polymorphism in sheep at the growth hormone locus is the result of variation in gene number, Anim. Biotechnol., 1990, vol. 1, no. 2, pp. 135–144.

    Article  CAS  Google Scholar 

  72. Venkatesh, B. and Brenner, S., Genomic structure and sequence of the pufferfish (Fugu rubripes) growth hormone-encoding gene: a comparative analysis of teleost growth hormone genes, Gene, 1997, vol. 187, no. 2, pp. 211–215.

    Article  CAS  PubMed  Google Scholar 

  73. Von Schalburg, K.R., Yazawa, R., de Boer, J., et al., Isolation, characterization and comparison of Atlantic and Chinook salmon growth hormone 1 and 2, BMC Genomics, 2008, vol. 9, art. ID 522. https://doi.org/10.1186/1471-2164-9-522

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  74. Wallis, M., Variable evolutionary rates in the molecular evolution of mammalian growth hormones, J. Mol. Evol., 1994, vol. 38, no. 6, pp. 619–627.

    Article  CAS  PubMed  Google Scholar 

  75. Wallis, M., The molecular evolution of vertebrate growth hormones: a pattern of near-stasis interrupted by sustained bursts of rapid change, J. Mol. Evol., 1996, vol. 43, no. 2, pp. 93–100.

    Article  CAS  PubMed  Google Scholar 

  76. Wallis, O.C. and Wallis, M., Cloning and characterisation of the rabbit growth hormone-encoding gene, Gene, 1995, vol. 163, no. 2, pp. 253–256.

    Article  CAS  PubMed  Google Scholar 

  77. Wallis, O.C. and Wallis, M., Molecular evolution of growth hormone (GH) in Cetartiodactyla: cloning and characterization of the gene encoding GH from a primitive ruminant, the chevrotain (Tragulus javanicus), Gen. Comp. Endocrinol., 2001, vol. 123, no. 1, pp. 62–72.

    Article  CAS  PubMed  Google Scholar 

  78. Wallis, O.C., Zhang, Y.P., and Wallis, M., Molecular evolution of GH in primates: characterisation of the GH genes from slow loris and marmoset defines an episode of rapid evolutionary change, J. Mol. Endocrinol., 2001, vol. 26, no. 3, pp. 249–258.

    Article  CAS  PubMed  Google Scholar 

  79. Westrich, K.M., Konkol, N.R., Matsuoka, M.P., and Phillips, R.B., Interspecific relationships among charrs based on phylogenetic analysis of nuclear growth hormone intron sequences, Environ. Biol. Fishes., 2002, vol. 64, nos. 1–3, pp. 217–222.

    Article  Google Scholar 

  80. Yamada, S., Hata, J., and Yamashita, S., Molecular cloning of fish Pit-1 cDNA and its functional binding to promoter of gene expressed in the pituitary, J. Biol. Chem., 1993, vol. 268, no. 32, pp. 24361–24366.

    CAS  PubMed  Google Scholar 

  81. Yamaguchi, K., Yasuda, A., Lewis, U.J., et al., The complete amino acid sequence of growth hormone of an elasmobranch, the blue shark (Prionace glauca), Gen. Comp. Endocrinol., 1989, vol. 73, no. 2, pp. 252–259.

    Article  CAS  PubMed  Google Scholar 

  82. Yamano, Y., Abe, M., Mikawa, S., et al., Structural analysis of repetitive DNA sequences in the goat growth hormone gene region, Agric. Biol. Chem., 1991, vol. 55, no. 3, pp. 633–639.

    CAS  PubMed  Google Scholar 

  83. Yang, B.-Y., Chan, K.-M., Lin, C.-M., and Chen, T.T., Characterization of rainbow trout (Oncorhynchus mykiss) growth hormone 1 gene and the promoter region of growth hormone 2 gene, Arch. Biochem. Biophys., 1997, vol. 340, no. 2, pp. 359–368.

    Article  CAS  PubMed  Google Scholar 

  84. Yasuda, A., Yamaguchi, K., Papkoff, H., et al., The complete amino acid sequence of growth hormone from the sea turtle (Chelonia mydas), Gen. Comp. Endocrinol., 1989, vol. 13, no. 2, pp. 242–251.

    Article  Google Scholar 

  85. Yowe, D.L. and Epping, R.J., Cloning of the barramundi growth hormone encoding gene: a comparative analysis of higher and lower vertebrate GH genes, Gene, 1995, vol. 162, no. 2, pp. 255–259.

    Article  CAS  PubMed  Google Scholar 

  86. Yuri, T., Kimball, R.T., Braun, E.L., and Braun, M.J., Duplication of accelerated evolution and growth hormone gene in passerine birds, Mol. Biol. Evol., 2008, vol. 25, no. 2, pp. 352–361.

    Article  CAS  PubMed  Google Scholar 

  87. Zhu, Z., He, L., and Chen, T.T., Primary-structural and evolutionary analyses of the growth-hormone gene from grass carp (Ctenopharyngodon idellus), Eur. J. Biochem., 1992, vol. 207, no. 2, pp. 643–648.

    Article  CAS  PubMed  Google Scholar 

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  1. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041, Vladivostok, Russia

    D. N. Kamenskaya & V. A. Brykov

  2. School of Natural Sciences, Far Eastern Federal University, 690012, Vladivostok, Russia

    V. A. Brykov

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Translated by E. Shvetsov

Invited paper published in connection with the 50th anniversary of the foundation of Zhirmunsky Institute of Marine Biology (now Zhirmunsky NSCMB).

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Kamenskaya, D.N., Brykov, V.A. Fish Growth Hormone Genes: Structure and Divergence. Russ J Mar Biol 46, 233–242 (2020). https://doi.org/10.1134/S1063074020040033

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