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Three-Component Condensation of 1,2,4-Triazol-3-amine with Cyclohexanone and ortho-Substituted Benzaldehydes

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Abstract

Three-component condensation of 1,2,4-triazol-3-amine with cyclohexanone and ortho-substituted benzaldehydes afforded mixtures of angularly and linearly fused aryl-substituted hexahydrotriazoloquinazolines and octahydrotriazoloquinazolines whose structure was determined by using one- and two-dimensional NMR spectroscopy. A probable scheme of product formation was proposed.

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References

  1. Al-Salahi, R.A., Alswaidan, I., Al-Omar, M.A., and Marzouk, M.S., Life Sci. J., 2013, vol. 10, no. 4, p. 2018.

    Google Scholar 

  2. Antipenko, L., Karpenko, A., Kovalenko, S., Katsev, A., Komarovska-Porokhnyavets, E., Novikov, V., and Chekotilo, A., Chem. Pharm. Bull., 2009, vol. 57, no. 6, p. 580.

    Article  CAS  PubMed  Google Scholar 

  3. Hamouda, A.M., Pharma Chem., 2014, vol. 6, no. 6, p. 346.

    Google Scholar 

  4. El-Hashash, M.A., Rizk, S.A., and El-Bassiouny, F.A., Global J. Health Sci., 2012, vol. 4, no. 1, p. 174.

    Google Scholar 

  5. Al-Salahi, R.A., Gamal-Eldeen, A.M., Alanazi, A.M., Al-Omar, M.A., Marzouk, M.A., and Fouda, M.M.G., Molecules, 2013, vol. 18, p. 1434.

    Article  CAS  PubMed  Google Scholar 

  6. Powles, S.B. and Yu, Q., Annu. Rev. Plant Biol., 2010, vol. 61, p. 317.

    Article  CAS  Google Scholar 

  7. Lahmidi, S., Elyoussfi, A., Dafali, A., Elmsellem, H., Sebbar, N.K., El Ouasif, L., Jilalat, A.E., El Mahi, V., Essassi, E.M., Abdel-Rahman, I., and Hammouti, B., J. Mater. Environ. Sci., 2017, vol. 8, no. 1, p. 225.

    CAS  Google Scholar 

  8. Vasil’kova, N.O., Ivonin, M.A., Matikenova, A.A., Burygin, G.L., Golubev, A.A., and Kriven’ko, A.P., Sbornik nauchnykh trudov po materialam mezhdunarodnoi nauchnoi konferentsii “Problemy i innovatsii” (Collection of Scientific Papers. Proc. Int. Scientific Conf. “Problems and Innovations”), Ivanovo: Nauchnyi Mir, 2015, vol. 1, no. 1, p. 131.

    Google Scholar 

  9. Vasil’kova, N.O., Ivonin, M.A., Burygin, G.L., Prilepskii, A.Yu., and Kriven’ko, A.P., Materialy VIMezhdunarodnoi nauchno-metodicheskoi konferentsii “Farmobrazovanie-2016” (Proc. VIth Int. Scientific Methodical Conf. “Pharmaceutical Education 2016”), Voronezh, 2016, p. 204.

    Google Scholar 

  10. Matveeva, A.A., Matikenova, A.A., Anis’kov, A.A., and Kriven’ko, A.P., Russ. J. Org. Chem., 2015, vol. 51, no. 3, p. 378.

    Article  CAS  Google Scholar 

  11. Vasil’kova, N.O. and Kriven’ko, A.P., Sbornik nauchnykh trudov. Mezhdunarodnoe nauchnoe izdanie (Collection of Scientific Papers. International Scientific Edition), Odessa: SWorld, 2015, p. 4.

    Google Scholar 

  12. Vasil’kova, N.O., Anis’kov, A.A., and Kriven’ko, A.P., Russ. J. Org. Chem., 2015, vol. 51, no. 12, p. 1766.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Chemistry, Chernyshevskii Saratov National Research State University, ul. Astrakhanskaya 83, Bld. 1, Saratov, 410012, Russia

    N. O. Vasil’kova, A. A. Anis’kov, V. V. Sorokin & A. P. Kriven’ko

Authors
  1. N. O. Vasil’kova
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  2. A. A. Anis’kov
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  3. V. V. Sorokin
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  4. A. P. Kriven’ko
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Correspondence to N. O. Vasil’kova.

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Original Russian Text © N.O. Vasil’kova, A.A. Anis’kov, V.V. Sorokin, A.P. Kriven’ko, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 6, pp. 928–931.

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Vasil’kova, N.O., Anis’kov, A.A., Sorokin, V.V. et al. Three-Component Condensation of 1,2,4-Triazol-3-amine with Cyclohexanone and ortho-Substituted Benzaldehydes. Russ J Org Chem 54, 933–937 (2018). https://doi.org/10.1134/S1070428018060179

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  • DOI: https://doi.org/10.1134/S1070428018060179

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