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Infection and Immunity, January 2006, p. 781-785, Vol. 74, No. 1
0019-9567/06/$08.00+0     doi:10.1128/IAI.74.1.781-785.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Molecular Characterization of the Escherichia coli Asymptomatic Bacteriuria Strain 83972: the Taming of a Pathogen

Microbial Adhesion Group, Centre for Biomedical Microbiology, BioCentrum-DTU, Technical University of Denmark, DK-2800 Lyngby, Denmark,¹ School of Molecular and Microbial Sciences, University of Queensland, Brisbane QLD 4072, Australia,² Institute of Laboratory Medicine, Section for Microbiology, Immunology and Glycobiology, Lund University, Sölvegatan 23, SE-223 62 Lund, Sweden³

Received 26 September 2005/ Accepted 5 October 2005

Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.

Editor: V. J. DiRita

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