Related Content
Search Google Scholar for:
More Information
Related Jobs from ScienceCareers
|
|
Science 13 September 1996: Vol. 273. no. 5281, pp. 1516 - 1517 DOI: 10.1126/science.273.5281.1516
|
|
Perspectives
Neil Risch, Kathleen Merikangas
The identification of the genetic basis of complex human diseases such as schizophrenia and diabetes has proven difficult. In their Perspective, Risch and Merikangas propose that we can best accomplish this goal by combining the power of the human genome project with association studies, a method for determining the basis of a genetic disease.
N. Risch is in the Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA. E-mail: risch{at}lahmed.stanford.edu. K. Merikangas is in the Departments of Epidemiology and Psychiatry Unit, Yale University School of Medicine, New Haven, CT 06510, USA. E-mail: kath{at}zeus.psych.yale.edu
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Addictions Biology: Haplotype-Based Analysis for 130 Candidate Genes on a Single Array.
- C. A. Hodgkinson, Q. Yuan, K. Xu, P.-H. Shen, E. Heinz, E. A. Lobos, E. B. Binder, J. Cubells, C. L. Ehlers, J. Gelernter, et al. (2008)
Alcohol Alcohol.
43, 505-515
| Abstract »
| Full Text »
| PDF »
- Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology.
- P. R Burton, A. L Hansell, I. Fortier, T. A Manolio, M. J Khoury, J. Little, and P. Elliott (2008)
Int. J. Epidemiol.
| Abstract »
| Full Text »
| PDF »
- Status and Prospects of Association Mapping in Plants.
- C. Zhu, M. Gore, E. S. Buckler, and J. Yu (2008)
The Plant Genome
1, 5-20
| Abstract »
| Full Text »
| PDF »
- The Genetic Architecture of Intracerebral Hemorrhage.
- N. S. Rost, S. M. Greenberg, and J. Rosand (2008)
Stroke
39, 2166-2173
| Abstract »
| Full Text »
| PDF »
- Autosomal dominant moyamoya disease maps to chromosome 17q25.3.
- Y. Mineharu, W. Liu, K. Inoue, N. Matsuura, S. Inoue, K. Takenaka, H. Ikeda, K. Houkin, Y. Takagi, K. Kikuta, et al. (2008)
Neurology
70, 2357-2363
| Abstract »
| Full Text »
| PDF »
- Genetics of Attention Deficit/Hyperactivity Disorder.
- D. Wallis, H. F. Russell, and M. Muenke (2008)
J. Pediatr. Psychol.
| Abstract »
| Full Text »
| PDF »
- Genetics of Osteoporosis: From Population Association to Individualized Prognosis of Fracture.
- T. V. Nguyen (2008)
IBMS BoneKEy
5, 212-221
| Full Text »
| PDF »
- Parathyroid hormone-responsive B1 gene is associated with premature ovarian failure.
- H. Kang, S. K. Lee, M.-H. Kim, J. Song, S. J. Bae, N. K. Kim, S.-H. Lee, and K. Kwack (2008)
Hum. Reprod.
23, 1457-1465
| Abstract »
| Full Text »
| PDF »
- The complex genetics of multiple sclerosis: pitfalls and prospects.
- S. Sawcer (2008)
Brain
| Abstract »
| Full Text »
| PDF »
- Linkage disequilibrium analyses within chromosome 19p in multiple sclerosis.
- T. Vyshkina and B. Kalman (2008)
Multiple Sclerosis
14, 433-439
| Abstract »
| PDF »
- Extent of Linkage Disequilibrium in Holstein Cattle in North America.
- M. Sargolzaei, F. S. Schenkel, G. B. Jansen, and L. R. Schaeffer (2008)
J Dairy Sci
91, 2106-2117
| Abstract »
| Full Text »
| PDF »
- Gene-Centric Genomewide Association Study via Entropy.
- Y. Cui, G. Kang, K. Sun, M. Qian, R. Romero, and W. Fu (2008)
Genetics
179, 637-650
| Abstract »
| Full Text »
| PDF »
- Association between apolipoprotein-{varepsilon}4 and long-term outcome after traumatic brain injury.
- A H P W.-v. Son, G M Ribbers, W C J Hop, C M van Duijn, and H J Stam (2008)
J. Neurol. Neurosurg. Psychiatry
79, 426-430
| Abstract »
| Full Text »
| PDF »
- Increasing power in association studies by using linkage disequilibrium structure and molecular function as prior information.
- E. Eskin (2008)
Genome Res.
18, 653-660
| Abstract »
| Full Text »
| PDF »
- Statistical Power of Expression Quantitative Trait Loci for Mapping of Complex Trait Loci in Natural Populations.
- P. Schliekelman (2008)
Genetics
178, 2201-2216
| Abstract »
| Full Text »
| PDF »
- Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis.
- J. B. J. van Meurs, T. A. Trikalinos, S. H. Ralston, S. Balcells, M. L. Brandi, K. Brixen, D. P. Kiel, B. L. Langdahl, P. Lips, O. Ljunggren, et al. (2008)
JAMA
299, 1277-1290
| Abstract »
| Full Text »
| PDF »
- Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
- B. Gold, T. Kirchhoff, S. Stefanov, J. Lautenberger, A. Viale, J. Garber, E. Friedman, S. Narod, A. B. Olshen, P. Gregersen, et al. (2008)
PNAS
105, 4340-4345
| Abstract »
| Full Text »
| PDF »
- Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA.
- T. Kawase, Y. Nannya, H. Torikai, G. Yamamoto, M. Onizuka, S. Morishima, K. Tsujimura, K. Miyamura, Y. Kodera, Y. Morishima, et al. (2008)
Blood
111, 3286-3294
| Abstract »
| Full Text »
| PDF »
- Genome-Wide Association for Methamphetamine Dependence: Convergent Results From 2 Samples.
- G. R. Uhl, T. Drgon, Q.-R. Liu, C. Johnson, D. Walther, T. Komiyama, M. Harano, Y. Sekine, T. Inada, N. Ozaki, et al. (2008)
Arch Gen Psychiatry
65, 345-355
| Abstract »
| Full Text »
| PDF »
- Linkage Disequilibrium Under Skewed Offspring Distribution Among Individuals in a Population.
- B. Eldon and J. Wakeley (2008)
Genetics
178, 1517-1532
| Abstract »
| Full Text »
| PDF »
- Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies.
- H. Zhong and R. L. Prentice (2008)
Biostat.
| Abstract »
| Full Text »
| PDF »
- A multimetric approach to analysis of genome-wide association by single markers and composite likelihood.
- J. Gibson, W. Tapper, D. Cox, W. Zhang, A. Pfeufer, C. Gieger, H.-E. Wichmann, S. Kaab, A. R. Collins, T. Meitinger, et al. (2008)
PNAS
105, 2592-2597
| Abstract »
| Full Text »
| PDF »
- High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
- N. Kato, T. Miyata, Y. Tabara, T. Katsuya, K. Yanai, H. Hanada, K. Kamide, J. Nakura, K. Kohara, F. Takeuchi, et al. (2008)
Hum. Mol. Genet.
17, 617-627
| Abstract »
| Full Text »
| PDF »
- Three lectures on case control genetic association analysis.
- W. Li (2008)
Brief Bioinform
9, 1-13
| Abstract »
| Full Text »
| PDF »
- Genetic Design and Statistical Power of Nested Association Mapping in Maize.
- J. Yu, J. B. Holland, M. D. McMullen, and E. S. Buckler (2008)
Genetics
178, 539-551
| Abstract »
| Full Text »
| PDF »
- Simple Formulas for Gauging the Potential Impacts of Population Stratification Bias.
- W.-C. Lee and L.-Y. Wang (2008)
Am. J. Epidemiol.
167, 86-89
| Abstract »
| Full Text »
| PDF »
- A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array.
- R. L. Hanson, C. Bogardus, D. Duggan, S. Kobes, M. Knowlton, A. M. Infante, L. Marovich, D. Benitez, L. J. Baier, and W. C. Knowler (2007)
Diabetes
56, 3045-3052
| Abstract »
| Full Text »
| PDF »
- Identification of Type 2 Diabetes Genes in Mexican Americans Through Genome-Wide Association Studies.
- M. G. Hayes, A. Pluzhnikov, K. Miyake, Y. Sun, M. C.Y. Ng, C. A. Roe, J. E. Below, R. I. Nicolae, A. Konkashbaev, G. I. Bell, et al. (2007)
Diabetes
56, 3033-3044
| Abstract »
| Full Text »
| PDF »
- Common pathways in Crohn's disease and other inflammatory diseases revealed by genomics.
- D. Massey and M. Parkes (2007)
Gut
56, 1489-1492
| Abstract »
| Full Text »
| PDF »
- Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits.
- A. Swaroop, K. E. Branham, W. Chen, and G. Abecasis (2007)
Hum. Mol. Genet.
16, R174-R182
| Abstract »
| Full Text »
| PDF »
- Successful design and conduct of genome-wide association studies.
- C. I. Amos (2007)
Hum. Mol. Genet.
16, R220-R225
| Abstract »
| Full Text »
| PDF »
- Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap project.
- Y. Nannya, K. Taura, M. Kurokawa, S. Chiba, and S. Ogawa (2007)
Hum. Mol. Genet.
16, 2494-2505
| Abstract »
| Full Text »
| PDF »
- The Roles of PAX6 and SOX2 in Myopia: Lessons from the 1958 British Birth Cohort.
- C. L. Simpson, P. Hysi, S. S. Bhattacharya, C. J. Hammond, A. Webster, C. S. Peckham, P. C. Sham, and J. S. Rahi (2007)
Invest. Ophthalmol. Vis. Sci.
48, 4421-4425
| Abstract »
| Full Text »
| PDF »
- Prediction of individual genetic risk to disease from genome-wide association studies.
- N. R. Wray, M. E. Goddard, and P. M. Visscher (2007)
Genome Res.
17, 1520-1528
| Abstract »
| Full Text »
| PDF »
- Genetic Susceptibility to Peripheral Arterial Disease: A Dark Corner in Vascular Biology.
- J. W. Knowles, T. L. Assimes, J. Li, T. Quertermous, and J. P. Cooke (2007)
Arterioscler. Thromb. Vasc. Biol.
27, 2068-2078
| Abstract »
| Full Text »
| PDF »
- Simulating association studies: a data-based resampling method for candidate regions or whole genome scans.
- F. A. Wright, H. Huang, X. Guan, K. Gamiel, C. Jeffries, W. T. Barry, F. Pardo-Manuel de Villena, P. F. Sullivan, K. C. Wilhelmsen, and F. Zou (2007)
Bioinformatics
23, 2581-2588
| Abstract »
| Full Text »
| PDF »
- Efficacy assessment of SNP sets for genome-wide disease association studies.
- A. Wollstein, A. Herrmann, M. Wittig, M. Nothnagel, A. Franke, P. Nurnberg, S. Schreiber, M. Krawczak, and J. Hampe (2007)
Nucleic Acids Res.
35, e113
| Abstract »
| Full Text »
| PDF »
- TRAF1-C5 as a Risk Locus for Rheumatoid Arthritis -- A Genomewide Study.
- R. M. Plenge, M. Seielstad, L. Padyukov, A. T. Lee, E. F. Remmers, B. Ding, A. Liew, H. Khalili, A. Chandrasekaran, L. R.L. Davies, et al. (2007)
N. Engl. J. Med.
357, 1199-1209
| Abstract »
| Full Text »
| PDF »
- Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study.
- The International Multiple Sclerosis Genetics Cons (2007)
N. Engl. J. Med.
357, 851-862
| Abstract »
| Full Text »
| PDF »
- Genomewide Association Analysis of Coronary Artery Disease.
- N. J. Samani, J. Erdmann, A. S. Hall, C. Hengstenberg, M. Mangino, B. Mayer, R. J. Dixon, T. Meitinger, P. Braund, H.-E. Wichmann, et al. (2007)
N. Engl. J. Med.
357, 443-453
| Abstract »
| Full Text »
| PDF »
- Association of AGTR1 With 18-Month Treatment Outcome in Late-Life Depression.
- D. G. Kondo, M. C. Speer, K. R. Krishnan, D. R. McQuoid, S. H. Slifer, C. F. Pieper, A. V. Billups, and D. C. Steffens (2007)
Am J Geriatr Psychiatry
15, 564-572
| Abstract »
| Full Text »
| PDF »
- Genetic association studies of interleukin-13 receptor {alpha}1 subunit gene polymorphisms in asthma and atopy.
- A. K. Konstantinidis, S. J. Barton, I. Sayers, I. A. Yang, J. L. Lordan, S. Rorke, J. B. Clough, S. T. Holgate, and J. W. Holloway (2007)
Eur. Respir. J.
30, 40-47
| Abstract »
| Full Text »
| PDF »
- Bayesian method for gene detection and mapping, using a case and control design and DNA pooling.
- T. Johnson (2007)
Biostat.
8, 546-565
| Abstract »
| Full Text »
| PDF »
- GPDTI: A Genetic Programming Decision Tree Induction method to find epistatic effects in common complex diseases.
- J. K. Estrada-Gil, J. C. Fernandez-Lopez, E. Hernandez-Lemus, I. Silva-Zolezzi, A. Hidalgo-Miranda, G. Jimenez-Sanchez, and E. E. Vallejo-Clemente (2007)
Bioinformatics
23, i167-i174
| Abstract »
| Full Text »
| PDF »
- Genetic Susceptibility, HIV Infection, and the Kidney.
- K. Kiryluk, J. Martino, and A. G. Gharavi (2007)
Clin. J. Am. Soc. Nephrol.
2, S25-S35
| Abstract »
| Full Text »
| PDF »
- Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance.
- M. J. Huentelman, A. Papassotiropoulos, D. W. Craig, F. J. Hoerndli, J. V. Pearson, K.-D. Huynh, J. Corneveaux, J. Hanggi, C. R.A. Mondadori, A. Buchmann, et al. (2007)
Hum. Mol. Genet.
16, 1469-1477
| Abstract »
| Full Text »
| PDF »
- Genetic Epidemiology of Obesity.
- W. Yang, T. Kelly, and J. He (2007)
Epidemiol. Rev.
| Abstract »
| Full Text »
| PDF »
- The Contribution of Methotrexate Exposure and Host Factors on Transcriptional Variance in Human Liver.
- G. S. Belinsky, A. L. Parke, Q. Huang, K. Blanchard, S. Jayadev, R. Stoll, M. Rothe, L. E. K. Achenie, R. R. Gupta, G. Y. Wu, et al. (2007)
Toxicol. Sci.
97, 582-594
| Abstract »
| Full Text »
| PDF »
- Quantitative Trait Loci for Fasting Glucose in Young Europeans Replicate Previous Findings for Type 2 Diabetes in 2q23-24 and Other Locations.
- D. Fradin, S. Heath, M. Lathrop, and P. Bougneres (2007)
Diabetes
56, 1742-1745
| Abstract »
| Full Text »
| PDF »
- A Bayesian Multilocus Association Method: Allowing for Higher-Order Interaction in Association Studies.
- A. Albrechtsen, S. Castella, G. Andersen, T. Hansen, O. Pedersen, and R. Nielsen (2007)
Genetics
176, 1197-1208
| Abstract »
| Full Text »
| PDF »
- Joint Estimates of Quantitative Trait Locus Effect and Frequency Using Synthetic Recombinant Populations of Drosophila melanogaster.
- S. J. Macdonald and A. D. Long (2007)
Genetics
176, 1261-1281
| Abstract »
| Full Text »
| PDF »
- IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis.
- S. Garnier, P. Dieude, L. Michou, S. Barbet, A. Tan, S. Lasbleiz, T. Bardin, B. Prum, F. Cornelis, and for ECRAF (2007)
Ann Rheum Dis
66, 828-831
| Abstract »
| Full Text »
| PDF »
- Colloquium Papers: Plant domestication, a unique opportunity to identify the genetic basis of adaptation.
- J. Ross-Ibarra, P. L. Morrell, and B. S. Gaut (2007)
PNAS
104, 8641-8648
| Abstract »
| Full Text »
| PDF »
- Evaluation of Genetic Variations in the Androgen and Estrogen Metabolic Pathways as Risk Factors for Sporadic and Familial Prostate Cancer.
- J. M. Cunningham, S. J. Hebbring, S. K. McDonnell, M. S. Cicek, G. B. Christensen, L. Wang, S. J. Jacobsen, J. R. Cerhan, M. L. Blute, D. J. Schaid, et al. (2007)
Cancer Epidemiol. Biomarkers Prev.
16, 969-978
| Abstract »
| Full Text »
| PDF »
- Variants in ARHGEF11, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians.
- L. Ma, R. L. Hanson, L. N. Que, A. M.G. Cali, M. Fu, J. L. Mack, A. M. Infante, S. Kobes, the International Type 2 Diabetes 1q Consortium, C. Bogardus, et al. (2007)
Diabetes
56, 1454-1459
| Abstract »
| Full Text »
| PDF »
- Genetic Variations Associated With Echocardiographic Left Ventricular Traits in Hypertensive Blacks.
- K. J. Meyers, T. H. Mosley, E. Fox, E. Boerwinkle, D. K. Arnett, R. B. Devereux, and S. L.R. Kardia (2007)
Hypertension
49, 992-999
| Abstract »
| Full Text »
| PDF »
- Renal Albumin Excretion: Twin Studies Identify Influences of Heredity, Environment, and Adrenergic Pathway Polymorphism.
- F. Rao, J. Wessel, G. Wen, L. Zhang, B. K. Rana, B. P. Kennedy, T. A. Greenwood, R. M. Salem, Y. Chen, S. Khandrika, et al. (2007)
Hypertension
49, 1015-1031
| Abstract »
| Full Text »
| PDF »
- Two Common Chromosome 8q24 Variants Are Associated with Increased Risk for Prostate Cancer.
- L. Wang, S. K. McDonnell, J. P. Slusser, S. J. Hebbring, J. M. Cunningham, S. J. Jacobsen, J. R. Cerhan, M. L. Blute, D. J. Schaid, and S. N. Thibodeau (2007)
Cancer Res.
67, 2944-2950
| Abstract »
| Full Text »
| PDF »
- Single-Nucleotide Polymorphisms and Lung Disease: Clinical Implications.
- S. J. Tebbutt, A. James, and P. D. Pare (2007)
Chest
131, 1216-1223
| Abstract »
| Full Text »
| PDF »
- Identification of PVT1 as a Candidate Gene for End-Stage Renal Disease in Type 2 Diabetes Using a Pooling-Based Genome-Wide Single Nucleotide Polymorphism Association Study.
- R. L. Hanson, D. W. Craig, M. P. Millis, K. A. Yeatts, S. Kobes, J. V. Pearson, A. M. Lee, W. C. Knowler, R. G. Nelson, and J. K. Wolford (2007)
Diabetes
56, 975-983
| Abstract »
| Full Text »
| PDF »
- Large scale genotype phenotype correlation analysis based on phylogenetic trees.
- F. Habib, A. D. Johnson, R. Bundschuh, and D. Janies (2007)
Bioinformatics
23, 785-788
| Abstract »
| Full Text »
| PDF »
- A Genome-Wide Linkage Scan for Diabetic Retinopathy Susceptibility Genes in Mexican Americans With Type 2 Diabetes From Starr County, Texas.
- D. M. Hallman, E. Boerwinkle, V. H. Gonzalez, B. E. K. Klein, R. Klein, and C. L. Hanis (2007)
Diabetes
56, 1167-1173
| Abstract »
| Full Text »
| PDF »
- Clinical and Genetic Correlates of Aldosterone-to-Renin Ratio and Relations to Blood Pressure in a Community Sample.
- C. Newton-Cheh, C.-Y. Guo, P. Gona, M. G. Larson, E. J. Benjamin, T. J. Wang, S. Kathiresan, C. J. O'Donnell, S. L. Musone, A. L. Camargo, et al. (2007)
Hypertension
49, 846-856
| Abstract »
| Full Text »
| PDF »
- Corin I555(P568) Allele Is Associated With Enhanced Cardiac Hypertrophic Response to Increased Systemic Afterload.
- J. E. Rame, M. H. Drazner, W. Post, R. Peshock, J. Lima, R. S. Cooper, and D. L. Dries (2007)
Hypertension
49, 857-864
| Abstract »
| Full Text »
| PDF »
- High density SNP association study of a major autism linkage region on chromosome 17.
- J. L. Stone, B. Merriman, R. M. Cantor, D. H. Geschwind, and S. F. Nelson (2007)
Hum. Mol. Genet.
16, 704-715
| Abstract »
| Full Text »
| PDF »
- The molecular epidemiology of lung cancer.
- A. G. Schwartz, G. M. Prysak, C. H. Bock, and M. L. Cote (2007)
Carcinogenesis
28, 507-518
| Abstract »
| Full Text »
| PDF »
- An Extension of the Transmission Disequilibrium Test Incorporating Imprinting.
- Y.-Q. Hu, J.-Y. Zhou, and W. K. Fung (2007)
Genetics
175, 1489-1504
| Abstract »
| Full Text »
| PDF »
- High-Resolution Mapping for Essential Hypertension Using Microsatellite Markers.
- K. Yatsu, N. Mizuki, N. Hirawa, A. Oka, N. Itoh, T. Yamane, M. Ogawa, T. Shiwa, Y. Tabara, S. Ohno, et al. (2007)
Hypertension
49, 446-452
| Abstract »
| Full Text »
| PDF »
- Homing in on Depression Genes.
- P. McGuffin, S. Cohen, and J. Knight (2007)
Am J Psychiatry
164, 195-197
| Full Text »
| PDF »
- Genetics in Psychosomatic Medicine: Research Designs and Statistical Approaches.
- J. M. McCaffery, H. Snieder, Y. Dong, and E. de Geus (2007)
Psychosom Med
69, 206-216
| Abstract »
| Full Text »
| PDF »
- Combining Sperm Typing and Linkage Disequilibrium Analyses Reveals Differences in Selective Pressures or Recombination Rates Across Human Populations.
- V. J. Clark, S. E. Ptak, I. Tiemann, Y. Qian, G. Coop, A. C. Stone, M. Przeworski, N. Arnheim, and A. D. Rienzo (2007)
Genetics
175, 795-804
| Abstract »
| Full Text »
| PDF »
- Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
- L. Michou, S. Lasbleiz, A.-C. Rat, P. Migliorini, A. Balsa, R. Westhovens, P. Barrera, H. Alves, C. Pierlot, E. Glikmans, et al. (2007)
PNAS
104, 1649-1654
| Abstract »
| Full Text »
| PDF »
- Genetics of Sarcoidosis: Candidate Genes and Genome Scans.
- M. C. Iannuzzi and B. A. Rybicki (2007)
Proceedings of the ATS
4, 108-116
| Abstract »
| Full Text »
| PDF »
- Marker-assisted selection to improve drought adaptation in maize: the backcross approach, perspectives, limitations, and alternatives.
- J.-M. Ribaut and M. Ragot (2007)
J. Exp. Bot.
58, 351-360
| Abstract »
| Full Text »
| PDF »
- Bayesian modeling for genetic association in case-control studies: accounting for unknown population substructure.
- L. Zhang, B. Mukherjee, M. Ghosh, and R. Wu (2006)
Statistical Modeling
6, 352-372
| Abstract »
| PDF »
- Genetic Associations in Preterm Birth: A Primer of Marker Selection, Study Design, and Data Analysis.
- R. Menon, S. J. Fortunato, P. Thorsen, and S. Williams (2006)
Reproductive Sciences
13, 531-541
| Abstract »
| PDF »
- Genetic association studies of complex neurological diseases..
- P M Abou-Sleiman, M G Hanna, and N W Wood (2006)
J. Neurol. Neurosurg. Psychiatry
77, 1302-1304
| Abstract »
| Full Text »
| PDF »
- Identifying genes for diabetic nephropathy--current difficulties and future directions.
- B. R. Conway, D. A. Savage, and A. Peter Maxwell (2006)
Nephrol. Dial. Transplant.
21, 3012-3017
| Full Text »
| PDF »
- Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives.
- E. L. Webb, M. F. Rudd, G. S. Sellick, R. El Galta, L. Bethke, W. Wood, O. Fletcher, S. Penegar, L. Withey, M. Qureshi, et al. (2006)
Hum. Mol. Genet.
15, 3263-3271
| Abstract »
| Full Text »
| PDF »
- Fine-mapping of coccidia-resistant quantitative trait Loci in chickens..
- E.-S. Kim, Y. H. Hong, W. Min, and H. S. Lillehoj (2006)
Poult. Sci.
85, 2028-2030
| Abstract »
| Full Text »
| PDF »
- The C677T Polymorphism in the Methylenetetrahydrofolate Reductase Gene (MTHFR), Maternal Use of Folic Acid Supplements, and Risk of Isolated Clubfoot: A Case-Parent-Triad Analysis.
- L. Sharp, Z. Miedzybrodzka, A. H. Cardy, J. Inglis, L. Madrigal, S. Barker, D. Chesney, C. Clark, and N. Maffulli (2006)
Am. J. Epidemiol.
164, 852-861
| Abstract »
| Full Text »
| PDF »
- Nonlinear Tests for Genomewide Association Studies.
- J. Zhao, L. Jin, and M. Xiong (2006)
Genetics
174, 1529-1538
| Abstract »
| Full Text »
| PDF »
- Genetic Approaches to Coronary Heart Disease.
- J. C. Cohen (2006)
J. Am. Coll. Cardiol.
48, A10-A14
| Abstract »
| Full Text »
| PDF »
|
|