SIGNAL TRANSDUCTION: Sweet Conundrum

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Science 7 March 2008:
Vol. 319. no. 5868, pp. 1348 - 1349
DOI: 10.1126/science.1155915

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Morris J. Birnbaum

High blood glucose concentration causes a transcription factor to be modified with a sugar moiety, triggering the liver to produce yet more glucose.

Institute of Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA. E-mail: birnbaum{at}mail.med.upenn.edu

REPORTS Hepatic Glucose Sensing via the CREB Coactivator CRTC2: Renaud Dentin, Susan Hedrick, Jianxin Xie, John Yates, III, and Marc Montminy (7 March 2008)
Science 319 (5868), 1402. [DOI: 10.1126/science.1151363]
| Abstract » | Full Text » | PDF » | Supporting Online Material »

EDITORS' CHOICE
Cell Signaling
Directly Modulating Glucose Homeostasis: L. Bryan Ray (11 March 2008)
Sci. Signal. 1 (10), ec93. [DOI: 10.1126/stke.110ec93]
| Abstract »

Science. ISSN 0036-8075 (print), 1095-9203 (online)

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