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Science 22 August 2008:
Vol. 321. no. 5892, p. 1040
DOI: 10.1126/science.1155006
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Technical Comments

Comment on "Protein Sequences from Mastodon and Tyrannosaurus rex Revealed by Mass Spectrometry"

Pavel A. Pevzner,* Sangtae Kim, Julio Ng

Asara et al. (Reports, 13 April 2007, p. 280) reported sequencing of Tyrannosaurus rex proteins and used them to establish the evolutionary relationships between birds and dinosaurs. We argue that the reported T. rex peptides may represent statistical artifacts and call for complete data release to enable experimental and computational verification of their findings.

Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, Mail Code 0404, La Jolla, CA 92093–0404, USA.

* To whom correspondence should be addressed. E-mail: ppevzner{at}cs.ucsd.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)