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Science 19 August 2005:
Vol. 309. no. 5738, pp. 1196 - 1198
DOI: 10.1126/science.1111420
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Perspectives

PHYSIOLOGY:
Biological Clocks Coordinately Keep Life on Time

Martha U. Gillette and Terrence J. Sejnowski

Many biological processes, including cell division, metabolism, and seasonal flowering, are controlled by cycles of activity. Mechanisms called biological clocks maintain these cycles. In their Perspective, Gillette and Sejnowski discuss how some clocks do not operate independently of others. Rather, clocks may interact such that the state of one system can alter another.

M. U. Gillette is in the Department of Cell and Developmental Biology and the Neuroscience Program, University of Illinois, Urbana-Champaign, IL 61801, USA. T. J. Sejnowski is in the Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA and Department of Biology, University of California, San Diego, La Jolla, CA 92093, USA. E-mail: terry{at}salk.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)