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Science 24 March 2000:
Vol. 287. no. 5461, pp. 2222 - 2224
DOI: 10.1126/science.287.5461.2222
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A Drosophila Complementary DNA Resource

Gerald M. Rubin, 123 Ling Hong, 13 Peter Brokstein, 13 Martha Evans-Holm, 13 Erwin Frise, 13 Mark Stapleton, 4 Damon A. Harvey 123

Collections of nonredundant, full-length complementary DNA (cDNA) clones for each of the model organisms and humans will be important resources for studies of gene structure and function. We describe a general strategy for producing such collections and its implementation, which so far has generated a set of cDNAs corresponding to over 40% of the genes in the fruit fly Drosophila melanogaster.

1 Berkeley Drosophila Genome Project,
2 Howard Hughes Medical Institute, and
3 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.
4 Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)