G. D. Schuler,
M. S. Boguski,
E. A. Stewart,
L. D. Stein,
G. Gyapay,
K. Rice,
R. E. White,
P. Rodriguez-Tomé,
A. Aggarwal,
E. Bajorek,
S. Bentolila,
B. B. Birren,
A. Butler,
A. B. Castle,
N. Chiannilkulchai,
A. Chu,
C. Clee,
S. Cowles,
P. J. R. Day,
T. Dibling,
N. Drouot,
I. Dunham,
S. Duprat,
C. East,
C. Edwards,
J.-B. Fan,
N. Fang,
C. Fizames,
C. Garrett,
L. Green,
D. Hadley,
M. Harris,
P. Harrison,
S. Brady,
A. Hicks,
E. Holloway,
L. Hui,
S. Hussain,
C. Louis-Dit-Sully,
J. Ma,
A. MacGilvery,
C. Mader,
A. Maratukulam,
T. C. Matise,
K. B. McKusick,
J. Morissette,
A. Mungall,
D. Muselet,
H. C. Nusbaum,
D. C. Page,
A. Peck,
S. Perkins,
M. Piercy,
F. Qin,
J. Quackenbush,
S. Ranby,
T. Reif,
S. Rozen,
C. Sanders,
X. She,
J. Silva,
D. K. Slonim,
C. Soderlund,
W.-L. Sun,
P. Tabar,
T. Thangarajah,
N. Vega-Czarny,
D. Vollrath,
S. Voyticky,
T. Wilmer,
X. Wu,
M. D. Adams,
C. Auffray,
N. A. R. Walter,
R. Brandon,
A. Dehejia,
P.
N. Goodfellow,
R. Houlgatte,
J. R. Hudson Jr.,
S. E. Ide,
K. R. Iorio,
W. Y. Lee,
N. Seki,
T. Nagase,
K. Ishikawa,
N. Nomura,
C. Phillips,
M. H. Polymeropoulos,
M. Sandusky,
K. Schmitt,
R. Berry,
K. Swanson,
R. Torres,
J.
C. Venter,
J. M. Sikela,
J. S. Beckmann,
J. Weissenbach,
R. M. Myers,
D. R. Cox,
M. R. James,
D. Bentley,
P. Deloukas,
E. S. Lander,
T. J. Hudson
The
human genome is thought to harbor 50,000 to 100,000 genes, of which
about half have been sampled to date in the form of expressed sequence
tags. An international consortium was organized to develop and map
gene-based sequence tagged site markers on a set of two radiation
hybrid panels and a yeast artificial chromosome library. More than
16,000 human genes have been mapped relative to a framework map that
contains about 1000 polymorphic genetic markers. The gene map unifies
the existing genetic and physical maps with the nucleotide and protein
sequence databases in a fashion that should speed the discovery of
genes underlying inherited human disease. The integrated resource is
available through a site on the World Wide Web at
http://www.ncbi.nlm.nih.gov/SCIENCE96/.
