This letter deals with a new way to explore in the neuromorphic engineering, the biomimetic artificial neuron using microfluidic techniques. This microfluidic device is able to mimic the electrical activity of one biological neuron. Usually these artificial neurons are made in Silicon but this device could replace the electronic one and solve most of the issues of biocompatibility. This microfluidic device is composed of 2 chambers for intra and extra-cellular modelling, different PDMS channels, selective permeable membrane for positive ionic exchange, quake valves and electrodes for recording the membrane potential. We obtain an electrical membrane potential similar to the biological neuron.