Large-area polymer replication for microfluidic devices

Mathias Heckele; Andreas Gerlach; Andreas E. Guber; Thomas Schaller

doi:10.1117/12.425380

5 April 2001 Large-area polymer replication for microfluidic devices

Mathias Heckele, Andreas Gerlach, Andreas E. Guber, Thomas Schaller

Proceedings Volume 4408, Design, Test, Integration, and Packaging of MEMS/MOEMS 2001; (2001) https://doi.org/10.1117/12.425380
Event: Design, Test, Integration, and Packaging of MEMS/MOEMS 2001, 2001, Cannes-Mandelieu, France

Abstract

A huge market development is expected for modern drug discovery and genomic analysis when rapid parallel analysis of a large number of samples gets available at affordable costs. The state of the art shows that low cost devices can be fabricated in mass production by micromolding of polymers. In close collaboration, Greiner Bio-One and Forschungszentrum Karlsruhe have developed a single-use plastic microfluidic capillary electrophoresis (CE) array in the standardized microplate footprint. This paper presents the results of experiences which show that hot embossing with a mechanically micromachined molding tool is the appropriate technology for low cost mass fabrication. A subsequent sealing of the microchannels allows sub-microliter sample volumes in 96- channel multiplexed microstructures.

Citation Download Citation

Mathias Heckele, Andreas Gerlach, Andreas E. Guber, and Thomas Schaller "Large-area polymer replication for microfluidic devices", Proc. SPIE 4408, Design, Test, Integration, and Packaging of MEMS/MOEMS 2001, (5 April 2001); https://doi.org/10.1117/12.425380

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