Cancer diagnostics by infrared spectroscopy

Martina Meinke; Ingo H. Gersonde; Uwe Bindig; Markus Mueller; Kurt Miller; Gerhard J. Mueller

doi:10.1117/12.409331

16 November 2000 Cancer diagnostics by infrared spectroscopy

Martina Meinke, Ingo H. Gersonde, Uwe Bindig, Markus Mueller, Kurt Miller, Gerhard J. Mueller

Proceedings Volume 4161, Optical Biopsy and Tissue Optics; (2000) https://doi.org/10.1117/12.409331
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

A diagnostic method to detect differences between diseased and normal tissue from bladder carcinoma by FTIR-microspectroscopy is described. Regions of interest on 10 micrometer thin tissue sections where mapped in transmission mode. After IR-Mapping, the samples have been analyzed with common pathological techniques. Quadratic discriminant as well as correlation analysis was applied to the obtained IR-maps allowing differentiation between cancerous and normal tissue. In the case of the correlation analyses it is further possible to distinguish between different types of tissue.

Citation Download Citation

Martina Meinke, Ingo H. Gersonde, Uwe Bindig, Markus Mueller, Kurt Miller, and Gerhard J. Mueller "Cancer diagnostics by infrared spectroscopy", Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); https://doi.org/10.1117/12.409331

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