A highly sensitive fluorescence sensor for adrenaline detection based on modified carbon quantum dots

Wei Wu; Liyun Ding; Haitao Lin; Sha Yu; Jun Huang; Zhilin Xia

doi:10.1117/12.2506345

15 November 2018 A highly sensitive fluorescence sensor for adrenaline detection based on modified carbon quantum dots

Wei Wu, Liyun Ding, Haitao Lin, Sha Yu, Jun Huang, Zhilin Xia

Proceedings Volume 10964, Tenth International Conference on Information Optics and Photonics; 109645F (2018) https://doi.org/10.1117/12.2506345
Event: Tenth International Conference on Information Optics and Photonics (CIOP 2018), 2018, Beijing, China

Abstract

Adrenaline (AD) plays a vital role in the functioning of the central nervous system and the cardiovascular systems. We proposed a fluorescence probe for adrenaline detection based on the modified carbon quantum dots (CQDs). Carbon quantum dots were synthesized by the hydrothermal method, in which citric acid was used as a carbon source, and then modified with ammonia solution. Fluorescence spectrophotometer, transmission electron microscope and Fourier infrared spectroscopy were used to characterize the modified CQDs, respectively. CQDs modified with ammonia have strong fluorescence intensity and emit blue light under ultraviolet light. The adrenaline was related to the quenching fluorescence of CQDs, which was caused by the electron transfer between CQDs and adrenaline quinone under alkaline conditions. The optimum pH value and reaction time of the adrenaline detection used by CQDs were determined to be 10.14 and 300 seconds, respectively. A good linear dependence between the fluorescence intensity ratio of the CQDs and adrenaline concentration(10~100uM) was found after the introduction of a modified Stern-Volmer equation.

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Wei Wu, Liyun Ding, Haitao Lin, Sha Yu, Jun Huang, and Zhilin Xia "A highly sensitive fluorescence sensor for adrenaline detection based on modified carbon quantum dots", Proc. SPIE 10964, Tenth International Conference on Information Optics and Photonics, 109645F (15 November 2018); https://doi.org/10.1117/12.2506345

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KEYWORDS

Luminescence

Carbon

Quantum dots

Fluorescence spectroscopy

Sensors

FT-IR spectroscopy

Spectrophotometry

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