A novel method for speckle reduction in optical coherence tomography by image registration

Hang Zhang; Zhongliang Li; Xiangzhao Wang; Nan Nan; Xuan Wang

doi:10.1117/12.2068846

17 September 2014 A novel method for speckle reduction in optical coherence tomography by image registration

Hang Zhang, Zhongliang Li, Xiangzhao Wang, Nan Nan, Xuan Wang

Proceedings Volume 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014); 92301Y (2014) https://doi.org/10.1117/12.2068846
Event: Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014), 2014, Wuhan, China

Abstract

Speckle noise is a key factor that can influence the image quality of optical coherence tomography (OCT). The averaging of multiple B-scans can effectively suppress the speckle noise. Because of the sample motion, the images have to be exactly aligned before averaging. In this paper, we propose a new method for OCT image registration that combines global and local registration. The method is able to align the large global displacements in axial and lateral directions, as well as local displacements caused by non-linear deformation between images. Compared with other OCT image registration methods, our method improves the signal-to-noise ratio and contrast-to-noise ratio.

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Hang Zhang, Zhongliang Li, Xiangzhao Wang, Nan Nan, and Xuan Wang "A novel method for speckle reduction in optical coherence tomography by image registration ", Proc. SPIE 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014), 92301Y (17 September 2014); https://doi.org/10.1117/12.2068846

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KEYWORDS

Image registration

Optical coherence tomography

Speckle

Signal to noise ratio

Affine motion model

Detection and tracking algorithms

Eye

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