Measurement of antideoxyribonuclease-B (ADN-B) appears to be the important test for the serological detection of streptococcal infection. We determined normal range of ADN-B titers of the serum specimens from various age groups of healthy children without the history of a recent 6 months' upper respiratory tract infection. We studied with lower dilution system of serum than the routine method. The upper limit of normal value was defined as 80th percentile of the titers of normal children.
The values for these groups are as follows<2 years:<10×, 3-5 years: 60×, 6-10 years: 160×, 11-15 years: 320×.
The paper shows that it is necessary to make the low titer investigation (<60×) on the examination of ADN-B value for children under 5 years old.