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Publication history
21 Dec 2007
Issue online:
25 Feb 2008
Dermatologic Surgery
Volume 34 Issue 3 Page 364-369, March 2008
To cite this article:
YANG-CHIH LIN MD, YU-HUNG WU MD, RICHARD K. SCHER FRCP (2008)
Nail Changes and Association of Osteoarthritis in Digital Myxoid Cyst
Dermatologic Surgery 34 (3)
, 364–369
doi:10.1111/j.1524-4725.2007.34070.x
Nail Changes and Association of Osteoarthritis in Digital Myxoid Cyst
Address correspondence and reprint requests to: Yu-Hung Wu, MD, Department of Dermatology, Mackay Memorial Hospital, 92, Sec 2, Chung-Shan N Road, Taipei, 10449, Taiwan, or e-mail: lin1234@ms2.mmh.org.twYang-Chih Lin, MD, Yu-Hung Wu, MD, and Richard K. Scher, FRCP, have indicated no significant interest with commercial supporters.
Abstract
BACKGROUND Digital myxoid cyst is relatively common on the digits. Nail changes and osteoarthritis are usually associated with this pathogenesis.
OBJECTIVE The objective was to clarify this relationship and its significance by analyzing the clinical, radiologic, and pathologic data.
METHODS AND MATERIALS Fifty-one patients with digital myxoid cysts were diagnosed and analyzed during a 5-year period.
RESULTS Thirty-eight (74.5%) of 51 patients showed radiologic evidence of primary interphalangeal joint osteoarthritis in the affected digits. Among the 39 cysts removed surgically and examined pathologically, 28 were myxomatous and 11 were ganglion. Different clinical manifestations of nail change, including longitudinal grooves (20 cases), concave canaliform dystrophy (9 cases), "washboard" transverse lines (5 cases), and longitudinal grooves with beaded ridges (1 case) were found.
CONCLUSION Osteoarthritis of the adjacent terminal joint is an important factor involved in forming digital myxoid cysts. Of the two cyst types, ganglion cysts are related to osteoarthritis more often than myxomatous cysts. Nail changes, secondary to matrix damage, are reliable clinical signs of underlying cyst formation. Understanding the pathogenesis of the digital myxoid cyst in relation to osteoarthritis and nail deformity helps inform the care of these patients.
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