Crystallographic characterization of the N-terminal domain of PEX1

Peroxisomal enzymes are responsible for several primary metabolism pathways, including β-oxidation and lipid biosynthesis. PEX1 and PEX6 are hexameric AAA-type ATPases and both are necessary for the import of more than 50 peroxisomal resident proteins from the cytosol into peroxisomes. In this study, PEX1 N-terminal domain crystals have been prepared. The crystals belong to space group P3₁ or P3₂, with unit-cell parameters a = b = 63.5 Å, c = 33.5 Å, and contain one protein molecule per crystallographic asymmetric unit. An intensity data set was collected to a resolution of 2.05 Å.