Scale Invariance in the Nonstationarity of Human Heart Rate

Pedro Bernaola-Galván, Plamen Ch. Ivanov, Luís A. Nunes Amaral, and H. Eugene Stanley
Phys. Rev. Lett. 87, 168105 – Published 2 October 2001
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Abstract

We introduce a segmentation algorithm to probe the temporal organization of heterogeneities in human heartbeat interval time series. We find that the lengths of segments with different local mean heart rates follow a power-law distribution and show that this scale-invariant structure is not a simple consequence of the long-range correlations present in the data. The differences in mean heart rates between consecutive segments display a common functional form, but with different parameters for healthy individuals and for heart-failure patients. These findings suggest that there is relevant physiological information hidden in the heterogeneities of the heartbeat time series.

  • Received 17 May 2000

DOI:https://doi.org/10.1103/PhysRevLett.87.168105

©2001 American Physical Society

Authors & Affiliations

Pedro Bernaola-Galván1,2, Plamen Ch. Ivanov1,3, Luís A. Nunes Amaral1,3, and H. Eugene Stanley1

  • 1Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215
  • 2Departamento de Física Aplicada II, Universidad de Málaga, E-29071, Spain
  • 3Cardiovascular Division, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215

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Vol. 87, Iss. 16 — 15 October 2001

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