Density-Polarity Coupling in Confined Active Polar Films: Asters, Spirals, and Biphasic Orientational Phases

Mathieu Dedenon, Claire A. Dessalles, Pau Guillamat, Aurélien Roux, Karsten Kruse, and Carles Blanch-Mercader
Phys. Rev. Lett. 131, 268301 – Published 28 December 2023

Abstract

Topological defects in active polar fluids can organize spontaneous flows and influence macroscopic density patterns. Both of them play an important role during animal development. Yet the influence of density on active flows is poorly understood. Motivated by experiments on cell monolayers confined to disks, we study the coupling between density and polar order for a compressible active polar fluid in the presence of a +1 topological defect. As in the experiments, we find a density-controlled spiral-to-aster transition. In addition, biphasic orientational phases emerge as a generic outcome of such coupling. Our results highlight the importance of density gradients as a potential mechanism for controlling flow and orientational patterns in biological systems.

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  • Received 28 July 2023
  • Revised 6 October 2023
  • Accepted 27 November 2023

DOI:https://doi.org/10.1103/PhysRevLett.131.268301

© 2023 American Physical Society

Physics Subject Headings (PhySH)

Physics of Living SystemsPolymers & Soft Matter

Authors & Affiliations

Mathieu Dedenon1,2, Claire A. Dessalles1, Pau Guillamat3, Aurélien Roux1, Karsten Kruse1,2,*, and Carles Blanch-Mercader4,†

  • 1Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland
  • 2Department of Theoretical Physics, University of Geneva, 1211 Geneva, Switzerland
  • 3Institute for Bioengineering of Catalonia, Barcelona Institute of Science and Technology, 08028 Barcelona, Spain
  • 4Laboratoire Physico-Chimie Curie, CNRS UMR168, Institut Curie, Université PSL, Sorbonne Université, 75005, Paris, France

  • *karsten.kruse@unige.ch
  • carles.blanch-mercader@curie.fr

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Issue

Vol. 131, Iss. 26 — 29 December 2023

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