A Physiologic and Pharmacologic Study of Olfactory Receptors
This extract was created in the absence of an abstract.
Excerpt
A PHYSIOLOGIC AND PHARMACOLOGIC STUDY OF OLFACTORY RECEPTORS
Olfactory receptor cells are bipolar neurons with ciliated terminals projecting into the mucus beyond the surrounding sustentacular cells. The axons of these neuroepithelial cells proceed a short distance through the region of basal cells and projections of the sustentacular cells, which are resting on a basement membrane, apparently already sheathed in small bundles (Gasser, 1956; de Lorenzo, 1963). These axons are the fibers of the primary olfactory nerve, wherein they are intimately bound by the large Schwann cells in bundles of up to many hundreds. There are no synapses or collateral connections until the fibers enter the glomeruli of the olfactory bulb in the central nervous system. Thus upon exposing the olfactory mucosa, one has millions of neural receptor cells that can be contacted in situ without further dissection. On the other hand, their axons can be got at intracranially without disturbing...
