Topic Introduction

Introduction to Genetic Association Studies

  1. Jo Knight
Adapted from Genetics of Complex Human Diseases (ed. Al-Chalabi and Almasy). CSHL Press, Cold Spring Harbor, NY, USA, 2009.

Abstract

Genetic association studies are used to find candidate genes or genome regions that contribute to a specific disease by testing for a correlation between disease status and genetic variation. This article provides a broad outline of the design and analysis of such studies, focusing on case–control studies in candidate genes or regions.

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  1. doi:10.1101/pdb.top068163 Cold Spring Harb Protoc 2012: pdb.top068163- © 2012 Cold Spring Harbor Laboratory Press
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