Morphogen Gradient Formation
- Correspondence: marcos.gonzalez{at}biochem.unige.ch
Abstract
How morphogen gradients are formed in target tissues is a key question for understanding the mechanisms of morphological patterning. Here, we review different mechanisms of morphogen gradient formation from theoretical and experimental points of view. First, a simple, comprehensive overview of the underlying biophysical principles of several mechanisms of gradient formation is provided. We then discuss the advantages and limitations of different experimental approaches to gradient formation analysis.
Footnotes
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Editors: James Briscoe, Peter Lawrence, and Jean-Paul Vincent
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Additional Perspectives on Generation and Interpretation of Morphogen Gradients available at www.cshperspectives.org
- Copyright © 2009 Cold Spring Harbor Laboratory Press; all rights reserved
