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Volume 9, Issue 6

A comparative genome analysis of the () class Open Access

A Correction to this article was published on 9 August 2023

Abstract

is recognized for its ability to anaerobically ferment dichloromethane (DCM), and a catabolic model has recently been proposed. is currently the only axenic representative of its class, the , according to the Genome Taxonomy Database. However, substantial additional diversity has been revealed in this lineage through culture-independent exploration of anoxic habitats. Here we performed a comparative analysis of 10 members of the representing three orders, and infer that anaerobic DCM degradation appears to be a recently acquired trait only present in some members of the order . Inferred traits common to the class include the use of amino acids as carbon and energy sources for growth, energy generation via a remarkable range of putative electron-bifurcating protein complexes and the presence of S-layers. The ability of to grow on serine without DCM was experimentally confirmed and a high abundance of the electron-bifurcating protein complexes and S-layer proteins was noted when this organism was grown on DCM. We suggest that members of the are low-abundance fermentative scavengers in anoxic habitats.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): comparative genomics , Dehalobacteriia , dichloromethane degradation , metabolic reconstruction and proteome
Funding
This study was supported by the:
  • Australian Research Council (Award FL150100038)
    • Principle Award Recipient: PhilipHugenholtz
© 2023 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.

Erratum

An erratum has been published for this content:
Corrigendum: ‘A comparative genome analysis of the ) class
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A comparative genome analysis of the Bacillota (Firmicutes) class Dehalobacteriia
M Gen 9, 001039 (2023); https://doi.org/10.1099/mgen.0.001039
/content/journal/mgen/10.1099/mgen.0.001039
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