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NCTC3000: a century of bacterial strain collecting leads to a rich genomic data resource
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Jo Dicks1
, Mohammed-Abbas Fazal1, Karen Oliver2, Nicholas E. Grayson2,†, Jake D. Turnbull1, Evangeline Bane1, Edward Burnett1, Ana Deheer-Graham1, Nancy Holroyd2, Dorota Kaushal1, Jacqueline Keane2, Gemma Langridge2,‡, Jane Lomax2, Hannah McGregor1, Steve Picton3, Michael Quail2, Deepak Singh3, Alan Tracey2, Jonas Korlach3, Julie E. Russell1, Sarah Alexander1 and Julian Parkhill2,§
Abstract
The National Collection of Type Cultures (NCTC) was founded on 1 January 1920 in order to fulfil a recognized need for a centralized repository for bacterial and fungal strains within the UK. It is among the longest-established collections of its kind anywhere in the world and today holds approximately 6000 type and reference bacterial strains – many of medical, scientific and veterinary importance – available to academic, health, food and veterinary institutions worldwide. Recently, a collaboration between NCTC, Pacific Biosciences and the Wellcome Sanger Institute established the NCTC3000 project to long-read sequence and assemble the genomes of up to 3000 NCTC strains. Here, at the beginning of the collection’s second century, we introduce the resulting NCTC3000 sequence read datasets, genome assemblies and annotations as a unique, historically and scientifically relevant resource for the benefit of the international bacterial research community.
- Received:
- Accepted:
- Published Online:
Keyword(s):
bacterial genomes
,
genome assemblies
,
National collection of type cultures
and
pacific bioscience long reads
© 2023 The Authors